Screen LibraryIron chelation therapy
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| Group Author: | |
|---|---|
| Published: |
Kluwer Academic/Plenum Pub.,
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| Publisher Address: | New York |
| Publication Dates: | c2002. |
| Literature type: | Book |
| Language: | English |
| Series: |
Advances in experimental medicine and biology ; 509 |
| Subjects: | |
| Carrier Form: | viii, 277 p.: ill. ; 26 cm. |
| ISBN: | 0306467852 |
| Index Number: | R589 |
| CLC: | R589.9 |
| Call Number: | R589.9/I712/ |
| Contents: |
Includes bibliographical references and index. Pathophysiology of iron overload -- Animal models of hereditary iron transport disorders -- Mechanism of iron toxicity -- Role of non-transferrin-bound iron in the pathogenesis of iron overload and toxicity -- Intacellular and extracellular labile iron pools -- Cardioprotective effect of iron chelators -- Chelation therapy in transfusional siderosis -- Results of long term iron Chelation treatment with deferoxamine -- Long term deferiprone chelation therapy -- Development of new iron chelators -- Iron chelators chemistry -- Structure-activity relationships among desazadesferrithiocin analogues -- ICL670A : preclinical profile -- Pyridoxal isonicotinoyl hydrazone and its analogues -- Novel strategies in iron chelation treatment -- Therapeutic potential of iron chelators in cancer therapy -- Antimalarial effect of iron chelators. |