Screen LibraryClinical and experimental toxicology of organophosphates and carbamates /
Saved in:
| Corporate Authors: | |
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| Group Author: | ; |
| Published: |
Butterworth Heinemann,
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| Publisher Address: | Oxford ; Boston : |
| Publication Dates: | 1992. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780750602716 |
| Carrier Form: | 1 online resource (xix, 641 pages) : illustrations |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9781483193656 1483193659 |
| Index Number: | RA1242 |
| CLC: | R996 |
| Contents: |
""Front Cover""; ""Clinical and Experimental Toxicology of Organophosphates and Carbamates""; ""Copyright Page""; ""Table of Contents""; ""Foreword""; ""Preface""; ""Contributors""; ""Abbreviations used in the text""; ""PART I: BASIC SCIENCE""; ""Chapter 1. Overview of the biological and clinical aspects of organophosphates and carbamates""; ""Chemistry""; ""Nomenclature of antiChEs""; ""Ecological aspects""; ""ChEs and cholinergic function""; ""Toxicology""; ""References""; ""Chapter 2. Biochemical determination of cholinesterase activity in biological fluids and tissues""; ""Introduction"" ""How to preserve sample quality""""Analytical methods""; ""References""; ""Chapter 3. Histochemical localization of cholinesterase in anticholinesterase poisoning""; ""Introduction""; ""Histochemical methods""; ""Cytochemical methods""; ""References""; ""Chapter 4. Pharmacology and toxicology of organophosphates""; ""Historical note""; ""Mechanism of action""; ""Cholinergic nerves""; ""Pharmacology""; ""Toxicology""; ""Therapeutic applications""; ""Acknowledgements""; ""References""; ""Chapter 5. Pharmacology and toxicology of carbamates""; ""Introduction"" ""Pharmacological action of CB drugs""""Toxicological action of CB insecticides""; ""References""; ""Chapter 6. Structure-activity relationships and anticholinesterase activity""; ""Introduction""; ""Kinetics of AChE inhibition""; ""Structure of AChE""; ""OP compounds""; ""Carbamates""; ""References""; ""PART 2: NEUROTOXICITY""; ""Chapter 7. Neurobehavioural toxicology of anticholinesterases""; ""Introduction""; ""Influence of antiChEs on sensory function""; ""Influence of antiChEs on cognitive function""; ""Influence of antiChEs on motor function"" ""Influence of antiChEs on affective function""""Discussion""; ""References""; ""Chapter 8. Central neurotoxicity and behavioural effects of anticholinesterases""; ""Introduction""; ""Cholinergic system in the CNS""; ""Biochemical effects of antiChEs on CNS""; ""Clinical and behavioural effects on CNS of antiChEs""; ""Conclusions""; ""References""; ""Chapter 9. Acute and subchronic neurotoxicity and cardiotoxicity of anticholinesterases""; ""Introduction""; ""Neurotoxicity""; ""Cardiac effects""; ""References"" ""Chapter 10. Molecular events in delayed neuropathy: experimental aspects of neuropathy target esterase""""Introduction""; ""A review of statements about NTE and OPIDP""; ""Molecular events at the target""; ""A review of questions about NTE and OPIDP""; ""Other recent studies of NTE""; ""General conclusion""; ""References""; ""Chapter 11. Validation of a rodent model of organophosphorus-induced delayed neuropathy""; ""Introduction""; ""Distribution of neuropathic damage in rat OPIDN""; ""Biochemical index of rat OPIDN""; ""Manipulation of OPIDN in the rat"" |