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Cocaine abuse : behavior, pharmacology, and clinical applications /

Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. Cocaine abuse results from a complex interplay of behavioral, pharmacological, and neurobiologi...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Higgins, Stephen T. (Editor); Katz, Jonathan L. (Editor)
Published: Academic Press,
Publisher Address: San Diego, Calif. :
Publication Dates: 1998.
Literature type: eBook
Language: English
Subjects:
Cocaine abuse > Pathophysiology.
Cocaine abuse > Treatment.
Cocaine > Psychological aspects.
Cocaine abuse.
Behavior > drug effects.
Cocaine.
Cocaine > pharmacology.
Cocaine-Related Disorders > therapy.
Cocaine habit.
HEALTH & FITNESS > Nervous System (incl. Brain) > Nervous System (incl. Brain)
MEDICAL > Neurology.
Cocai ne.
Verslaving.
Electronic books.
Online Access: http://www.sciencedirect.com/science/book/9780123473608
Summary: Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. Cocaine abuse results from a complex interplay of behavioral, pharmacological, and neurobiological determinants. While a complete understanding of cocaine abuse is currently beyond us, significant progress has been made in preclinical research on fundamental determinants of this disorder. These advances are critically reviewed in the first section of this volume. Important advances also have.
Carrier Form: 1 online resource (xxiv, 445 pages) : illustrations
Bibliography: Includes bibliographical references and index.
ISBN: 9780080529264
0080529267
9780123473608
0123473608
Index Number: RC568
CLC: R996
Contents: Basic pharmacological mechanisms of cocaine -- Neuroanatomical bases of the reinforcing stimulus effects of cocaine -- Behavioral pharmacology of cocaine and the determinants of abuse liability -- Behavioral-environmental determinants of the reinforcing functions of cocaine -- Tolerance and sensitization to cocaine: an integrated view -- Preclinical evaluation of pharmacotherapies for cocaine abuse -- Prenatal exposure to cocaine -- Cocaine self-administration research: implications for rational pharmacotherapy -- Evaluation of potential pharmacotherapies: response to cocaine challenge in the human laboratory -- Controlled laboratory studies on the effects of cocaine in combination with other commonly abused drugs in humans -- Cocaine effects on brain function -- Contribution of genetic factors in cocaine and other drug abuse -- Vulnerability to cocaine abuse -- Treating cocaine abuse: what does research tell us? -- Treatment of cocaine abuse in methadone maintenance patients -- Relapse to cocaine use -- Cocaine legalization: designing the experiments.

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