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Platelet proteomics principles, analysis, and applications /

The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential appli...

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Bibliographic Details
Corporate Authors: Wiley InterScience Online service
Group Author: García, Ángel, 1968; Senis, Yotis A., 1970
Published:
Literature type: Electronic eBook
Language: English
Series: Wiley-Interscience series on mass spectrometry
Subjects:
Blood platelets
Proteomics
Blood Platelets > physiology
Cardiovascular Diseases > physiopathology
Proteomics > methods
Thrombosis > physiopathology
Physiology
Science
Natural history
MEDICAL > Physiology
SCIENCE > Life Sciences > Human Anatomy & Physiology
Electronic books
Online Access: http://onlinelibrary.wiley.com/book/10.1002/9780470940297
Summary: The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational modifications (PTMs) analysis in platelets. The second part of the book focuses on the main research done so far on platelet proteomics. This includes general proteome mapping by non-gel based separat.
Carrier Form: 1 online resource (xx, 403 pages) : illustrations.
Bibliography: Includes bibliographical references and index.
ISBN: 9780470940297 (electronic bk.)
0470940298 (electronic bk.)
9780470940280 (electronic bk.)
047094028X (electronic bk.)
Index Number: QP97
CLC: R558
Contents: Platelets and their role in thrombotic and cardiovascular disease : the impact of proteomic analysis / by Ronald Stanley & Jon Gibbins -- Mass spectrometry-based proteomics : general overview, and PTMS analysis in the context of platelet research / by Julia Burkhart & Albert Sickmann -- Sample preparation variables in platelet proteomics for biomarker research / by Maria Zellner and Rudolf Oehler -- Two-dimensional gel electrophoresis : basic principles and application to platelet signaling studies / by Ángel García -- The platelet membrane proteome / by Yotis A. Senis -- Organellar prot

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