Screen LibraryClearance of dying cells in healthy and diseased immune systems
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Published by Blackwell Pub. on behalf of the New York Academy of Sciences,
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| Publisher Address: | Boston, Mass. |
| Publication Dates: | 2010. |
| Literature type: | Book |
| Language: | English |
| Series: |
Annals of the New York Academy of Sciences ; v. 1209 |
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| Carrier Form: | 126 p.: ill. ; 25 cm. |
| ISBN: |
9781573317979 1573317977 |
| Index Number: | R392 |
| CLC: | R392.12 |
| Call Number: | R392.12/C623 |
| Contents: |
Cover title. Papers presented at a conference entitled "Clearance of Dying Cells in a Healthy and Diseased Immune System" held May 9-11, 2010 in Jerusalem, Israel. Includes bibliographical references. What do we mean when we write "senescence," "apoptosis," "necrosis," or "clearance of dying cells"? -- Apoptosis and autoimmune diseases -- Anti-inflammatory functions of the "apoptotic" caspases -- TAM receptors and the clearance of apoptotic cells -- ELMO1 signaling in apoptotic germ cell clearance and spermatogenesis -- Immune regulation by apoptotic cell clearance -- Role of class A human thrombospondins in the clearance of dying cells and tolerance induction -- Apoptotic mimicry: phosphatidylserine-mediated macropinocytosis of vaccinia virus -- Responding to infection and apoptosis: a t "The mode of death and the clearance of dying cells has a tremendous impact on immune tolerance and alters the clearance of dying cells, which may lead to autoimmunity and persistent inflammation. Inflammatory and "dangerous" modes of death influence the process of clearance and have a crucial role in cancer and interaction with organisms that may mimic molecules appearing dying cells. These observation lead to the need of an exchange emphasizing the mammalian immune system in the context of diseases, such as inflammatory and autoimmune diseases, cancer, and infections. This volume explores |