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2-butenal

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Bibliographic Details
Main Authors: Kielhorn J
Corporate Authors: United Nations Environment Programme; International Labour Organisation; International Program on Chemical Safety; Inter-Organization Programme for the Sound Management of Chemicals; World Health Organization
Group Author: Ziegler-Skylakakis K; Mangelsdorf I
Published: World Health Organization,
Publisher Address: Geneva
Publication Dates: c2008.
Literature type: Book
Language: English
French
Spanish
Series: Concise international chemical assessment document ; 74
Subjects:
Crotonaldehyde > Toxicology
Crotonaldehyde > Physiological effect
Aldehydes > adverse effects
Aldehydes > toxicity
Aldehydes > pharmacokinetics
Environmental Exposure
Risk assessment
Crotonaldehyde > Environmental aspects
Carrier Form: vi, 47 p.: ill. ; 30 cm.
Publication Frequency: Also available online.
ISBN: 9789241530743
924153074X
Index Number: X78
CLC: X78
Call Number: X78/K472
Contents: Donation.
"IPCS, International Programme on Chemical Safety"--Cover.
"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization, and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals."
Includes bibliographical references (p. 32-38).
Identity and physical/chemical properties -- Analytical methods -- Sources of human and environmental exposure -- Environmental transport, distribution, transformation and accumulation -- Environmental levels and human exposure -- Comparative kinetics and metabolism in laboratory animals and humans -- Effects on laboratory mammals and in vitro test systems -- Effects on humans -- Effects on other organisms in the laboratory and field -- Effects evaluation -- Previous evaluations by IOMC bodies.
2-Butenal (also known as crotonaldehyde) is an ab-unsaturated aldehyde and consequently a very reactive compound. It is a chemical intermediate used chiefly in the manufacture of sorbates, solvents, and, to a lesser extent, pharmaceutical products and aroma chemicals. This publication studies the pharmacokinetics, environmental exposure, chemical toxicology and carcinogenicity of 2-butenal. However, to enable an understanding and evaluation of this aldehyde in the context of environmental health, other aldehydes, such as formaldehyde, acetaldehyde, and acrolein, are mentioned for comparison.

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