Screen LibraryGalanin
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| Corporate Authors: | |
|---|---|
| Group Author: | |
| Published: |
Springer,
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| Publisher Address: | Basel |
| Publication Dates: | c2010. |
| Literature type: | Book |
| Language: | English |
| Series: |
Experientia supplementum ; v. 102 |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1007/978-3-0346-0228-0 |
| Carrier Form: | 1 online resource (x, 285 p.): |
| ISBN: |
9783034602280 (electronic bk.) 3034602286 (electronic bk.) |
| Index Number: | Q51 |
| CLC: |
Q51 R977.6 |
| Contents: |
Includes bibliographical references and index. Galanin; Contents; Contributors; Galanin: A Multitalented Neuropeptide; Galanin, Galanin Receptors, and Drug Targets; Galanin Acts as a Trophic Factor to the Central and Peripheral Nervous Systems; Galanin and Spinal Pain Mechanisms: Past, Present, and Future; Galanin Family of Peptides in Skin Function; Galanin in Glia: Expression and Potential Roles in the CNS; Galanin and the Neuroendocrine Axes; Galanin and Consummatory Behavior: Special Relationship with Dietary Fat, Alcohol and Circulating Lipids. Galanin is a neuropeptide found both in the central and peripheral nervous system. The 29-amino acid peptide (named after its N-terminal glycine and C-terminal alanine) was identified in 1983 by its C-terminal amidation. This 'reverse' approach, that is to discover a substance through a distinct chemical feature, and only subsequently to characterize its biological activity, was novel and has been successful in the identification of several other peptides. After the structure of galanin was determined in 1983, functional studies were performed with material purified from natural sources until. |