Characterization, regulation, and interactions within the protease web /
The KLK proteins and their encoding genes are increasingly attracting attention among scientists and clinicians worldwide as they represent interesting and functionally distinct biomarkers both under physiological and pathophysiological conditions. This volume on kallikrein-related peptidases (KLKs)...
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Corporate Authors: | |
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Group Author: | ; ; ; |
Published: |
De Gruyter,
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Publisher Address: | Berlin : |
Publication Dates: |
[2012] ©2013 |
Literature type: | eBook |
Language: | English |
Series: |
Kallikrein-related peptidases ;
Volume 1 |
Subjects: | |
Online Access: |
http://dx.doi.org/10.1515/9783110260373 http://www.degruyter.com/doc/cover/9783110260373.jpg |
Summary: |
The KLK proteins and their encoding genes are increasingly attracting attention among scientists and clinicians worldwide as they represent interesting and functionally distinct biomarkers both under physiological and pathophysiological conditions. This volume on kallikrein-related peptidases (KLKs) reviews the characterization, regulation, and interactions of these proteases within the protease web. |
Carrier Form: | 1 online resource (426 pages). |
ISBN: | 9783110260373(electronic bk.) |
Index Number: | QP609 |
CLC: | Q556 |
Contents: |
Frontmatter -- Preface -- List of contributing authors -- Table of Contents -- Introduction to Volume 1: Kallikrein-related Peptidases. Characterization, Regulation, and Interactions Within the Protease Web -- 1 Genomic Structure of the KLK Locus -- 2 Single Nucleotide Polymorphisms in the Human KLK Locus and Their Implication in Various Diseases -- 3 Evolution of Kallikrein-related Peptidases -- 4 Structural Aspects of Kallikrein-related Peptidases -- 5 Molecular Recognition Properties of Kallikrein-related Peptidases on Synthetic and Endogenous Substrates -- 6 Natural, Engineered and Synthetic Inhibitors of Kallikrein-related Peptidases -- 7 Kallikrein-related Peptidases as Pharmaceutical Targets -- 8 Expression of Kallikrein-related Peptidases under (Patho-)Physiological Conditions -- 9 Kallikrein-related Peptidases within the Proteolytic Web -- 10 Kallikrein-Kinin Cascade: Bioregulation by Human Tissue Kallikrein 1 (hK1, KLK1) -- 11 Role of KLK4 in Dental Enamel Formation -- 12 Kallikrein-related Peptidases and Semen -- 13 Kallikrein-related Peptidases and Inhibitors of the Skin -- 14 Physiological and Pathophysiological Roles of Kallikrein-related Peptidases in the Central Nervous System -- 15 Kallikrein-related Peptidases (KLKs), Proteinase-mediated Signaling and Proteinase-activated Receptors (PARs) -- Index |