Screen LibraryBehavioral neurobiology of alcohol addiction /
The question of how alcohol alters mood states and why this may end up becoming an addiction has puzzled alcohol researchers for decades. In this volume, a group of highly distinguished experts and leaders in alcohol addiction research presents our current state of knowledge and remaining research c...
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| Corporate Authors: | |
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| Group Author: | ; |
| Published: |
Springer,
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| Publisher Address: | Berlin ; New York : |
| Publication Dates: | 2013. |
| Literature type: | eBook |
| Language: | English |
| Series: |
Current topics in behavioral neurosciences,
13 |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1007/978-3-642-28720-6 |
| Summary: |
The question of how alcohol alters mood states and why this may end up becoming an addiction has puzzled alcohol researchers for decades. In this volume, a group of highly distinguished experts and leaders in alcohol addiction research presents our current state of knowledge and remaining research challenges, as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a broad scientifically minded audience. Five Current Topics are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion substantially brought alcohol research forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs. |
| Carrier Form: | 1 online resource. |
| Bibliography: | Includes bibliographical references. |
| ISBN: |
9783642287206 (electronic bk.) 3642287204 (electronic bk.) |
| Index Number: | RC565 |
| CLC: | R749.6 |
| Contents: |
Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit Disorder / Synaptic Effects Induced by Alcohol / Signaling Pathways Mediating Alcohol Effects / Neurocircuitry Involved in the Development of Alcohol Addiction: The Dopamine System and its Access Points / What is in that Drink: The Biological Actions of Ethanol, Acetaldehyde, and Salsolinol / Modeling the Diagnostic Criteria for Alcohol Dependence with Genetic Animal Models / Non-Human Primate Models of Alcohol-Related Phenotypes: The Influence of Genetic and Environmental Factors / Genetically Selected Alcohol Preferring Rats to Model Human Alcoholism / Advanced Transgenic Approaches to Understand Alcohol-Related Phenotypes in Animals / Modeling Alcohol Self-Administration in the Human Laboratory / Animal Models of Excessive Alcohol Consumption in Rodents / Modeling Relapse Situations in the Human Laboratory / Modeling Relapse in Animals / Invertebrate Models of Alcoholism / The Dopamine System in Mediating Alcohol Effects in Humans / Stimulant and Sedative Effects of Alcohol / Chronic Alcohol Consumption, Abstinence and Relapse: Brain Proton Magnetic Resonance Spectroscopy Studies in Animals and Humans / Translational Approaches to Medication Development / New Pharmacological Treatment Strategies for Relapse Prevention / The Challenge of Studying Parallel Behaviors in Humans and Animal Models / A Translational Approach to Novel Medication Development for Protracted Abstinence / New Approaches to Addiction Treatment Based on Learning and Memory / Adolescent Substance Misuse: Neurobiology and Evidence-Based Interventions / Deep Brain Stimulation as a Therapy for Alcohol Addiction / |