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Metabolism of drugs and other xenobiotics

A practice-oriented desktop reference for toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part briefly reviews the main enzyme systems involved in biotransformation and...

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Bibliographic Details
Corporate Authors: Wiley InterScience Online service
Group Author: Anzenbacher, Pavel; Zanger, Ulrich M., 1955
Published:
Literature type: Electronic eBook
Language: English
Subjects:
Xenobiotics > metabolism
Biotransformation Metabolism
Toxicology
Biotransformation > physiology
Biological Agents > metabolism
Environmental Pollutants > metabolism
Pharmaceutical Preparations > metabolism
Pharmacokinetics
Electronic books
Online Access: http://onlinelibrary.wiley.com/book/10.1002/9783527630905
Summary: A practice-oriented desktop reference for toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part briefly reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making thi
Carrier Form: 1 online resource (734 p.)
Bibliography: Includes bibliographical references and index.
ISBN: 9783527630905 (electronic bk.)
3527630902 (electronic bk.)
9783527329038 (Cloth)
352732903X (Cloth)
9783527630912 (ePDF)
3527630910 (ePDF)
9783527646326 (ePub)
3527646329 (ePub)
9783527646333 (mobi)
3527646337 (mobi)
9781280665653 (MyiLibrary)
1280665653 (MyiLibrary)
Index Number: RA1211
CLC: R914
Contents: Front Matter -- Biochemistry and Molecular Genetics of Drug Metabolism. Drug-Metabolizing Enzymes₆An Overview / Pavel Anzenbacher, Eva Anzenbacherov̀ -- Cytochromes P450 / F Peter Guengerich -- UDP-Glucuronosyltransferases / Christian P Strassburg, Sandra Kalthoff -- Sulfotransferases / Michael W H Coughtrie -- Glutathione -Transferases / Miroslav Dostalek, Anna-Katarina Stark -- Hydrolytic Enzymes / Bingfang Yan -- Transporting Systems / Anne T Nies, Claudia Resch, Tadashi Namisaki -- Transcriptional Regulation of Human Drug-Metabolizing Cytochrome P450 Enzymes / Zdenek Dvorak -- Importa

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