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Perspectives in Cancer Prevention : Translational Cancer Research /

"Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory or population studies into clinical application to reduce incidence of cancer , morbidity and mo...

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Group Author: Sudhakaran, Perumana R. (Editor); Oommen, Oommen V. (Editor); Pillai, M. Radhakrishna (Editor); Rashid, Anis (Contributor); Kumar, T.R. Santhosh (Contributor); Sreekanth, Chanickal N. (Contributor); Bava, Smitha V. (Contributor); Thulasidasan, Arun Kumar T. (Contributor); Anto, Nikhil P. (Contributor); Cheriyan, Vino T. (Contributor); Puliyappadamba, Vineshkumar T. (Contributor); Menon, Sajna G. (Contributor); Ravichandran, Santhosh D. (Contributor); Anto, Ruby John (Contributor); Nagini, Siddavaram (Contributor); Priyadarsini, Ramamurthi Vidya (Contributor); Chandel, Madhu (Contributor); Sharma, Upendra (Contributor); Kumar, Neeraj (Contributor); Singh, Bikram (Contributor); Kaur, Satwinderjeet (Contributor); Subramaniam, Aruljothi (Contributor); Shanmugam, Muthu K. (Contributor); Perumal, Ekambaram (Contributor); Li, Feng (Contributor); Nachiyappan, Alamelu (Contributor); Kumar, Alan P. (Contributor); Tan, Benny K-H (Contributor); Sethi, Gautam (Contributor); Trivedi, Seema (Contributor); Awasthi, Yogesh C. (Contributor); Jaiswal, Shailesh (Contributor); Sahu, Mukesh (Contributor); Sharma, Abha (Contributor); Sharma, Rajendra (Contributor); Athira, A.P. (Contributor); Kiran, M.S. (Contributor); Stanley, Jone A. (Contributor); Neelamohan, Ramalingam (Contributor); Suthagar, Esakky (Contributor); Annapoorna, Kannan (Contributor); Sharmila, Sridharan (Contributor); Jayakumar, Jayaraman (Contributor); Srinivasan, Narasimhan (Contributor); Banu, Sakhila K. (Contributor); Chandrasekaran, Maharajan (Contributor); Aruldhas, Michael M. (Contributor); Riyasdeen, Anvarbatcha (Contributor); Loganathan, Rangasamy (Contributor); Palaniandavar, Mallayan (Contributor); Akbarsha, Mohammad A. (Contributor); Dixit, Ruhi (Contributor); Shukla, V. K. (Contributor); Fila, Marcus James (Contributor)
Published: Springer India,
Publisher Address: New Delhi, India :
Publication Dates: [2014]
Literature type: Book
Language: English
Subjects:
Cancer > Prevention.
Summary: "Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory or population studies into clinical application to reduce incidence of cancer , morbidity and mortality. It is becoming increasingly evident that cancer is a preventable disease. The IVth International Symposium on Translational Cancer Research held in Udaipur, India in December 2011, discussed various aspects of the biological processes in cancer cells and approaches to cancer prevention. A few contributions from this meeting are presented in this book, providing an in depth analysis of data on cancer prevention and therapeutics. These contributions are either critical reviews or research reports. The topics discussed include evidence-based nutritional recommendations for cancer patients and survivors, risk factors such as stress, enrichment of tumour stem cells by anticancer drug treatment contributing to tumour recurrence and the mechanism of anticancer effects of various natural products. Chemosensitizing effect of curcumin, anti-cancer effect of products from neem, action of sulforaphane and cytotoxic effect of a number of novel synthetic coordination complexes of trace metals have been discussed. Novel molecular targets of angiogenesis and molecular basis of the gender bias to thyroid cancer have also been discussed. This book provides useful information on translational cancer research to clinicians and biomedical scientists."--Back cover.
Carrier Form: xii, 168 pages : illustrations ; 26 cm
Bibliography: Includes bibliographical references and author index.
ISBN: 813221532X
9788132215325 (hardback) :
Index Number: RC 268
CLC: R730.1
Call Number: R730.1/P467-1
Contents: 1. Nutrition in Cancer: Evidence-Based Nutrition Recommendations in Cancer Patients and Survivors / Anis Rashid -- 2. Tumor Stem Cell Enrichment by Anticancer Drugs: A Potential Mechanism of Tumor Recurrence / T.R. Santhosh Kumar and M. Radhakrishna Pillai -- 3. Curcumin: A Potent Candidate to be Evaluated as a Chemosensitizer in Paclitaxel Chemotherapy Against Cervical Cancer / Chanickal N. Sreekanth, Smitha V. Bava, Arun Kumar T. Thulasidasan, Nikhil P. Anto, Vino T. Cheriyan, Vineshkumar T. Puliyappadamba, Sajna G. Menon, Santhosh D. Ravichandran, and Ruby John Anto -- 4. Azadirachta indica (Neem) and Neem Limonoids as Anticancer Agents: Molecular Mechanisms and Targets / Siddawaram Nagini and Ramamurthi Vidya Priyadarsini -- 5. In Vitro Studies on the Antioxidant/Antigenotoxic Potential of Aqueous Fraction from Anthocephalus cadamba Bark / Madhu Chandel, Upendra Sharma, Neeraj Kumar, Bikram Singh, and Satwinderjeet Kaur -- 6. Possible Involvement of Signal Transducer and Activator of Transcription-3 (STAT3) Signaling Pathway in the Initiation and Progression of Hepatocellular Carcinoma / Aruljothi Subramaniam, Muthu K. Shanmugam, Ekambaram Perumal, Feng Li, Alamelu Nachiyappan, Alan P. Kumar, Benny K.H. Tan, and Gautam Sethi -- 7. Simple Sequence Repeats In 5' and 3' Flanking Sequences of Cell Cycle Genes / Seema Trivedi -- 8. Mechanisms of Chemopreventive Activity of Sulforaphane / Yogesh C. Awasthi, Shailesh Jaiswal, Mukesh Sahu, Abha Sharma, and Rajendra Sharma -- 9. Reciprocal Relationship Between VE-Cadherin and Matrix Metalloproteinase Expression in Endothelial Cells and Its Implications to Angiogenesis / A.P. Athria, M.S. Kiran, and P.R. Sudhakaran -- 10. Androgen Receptor Expression in Human Thyroid Cancer Tissues: A Potential Mechanism Underlying the Gender Bias in the Incidence of Thyroid Cancers / Jone A. Stanley, Ramalingam Neelamohan, Esakky Suthagar, Kannan Annapoorna, Sridharan Sharmila, Jayaraman Jayakumar, Narasimhan Srinivasan, Sakhila K. Banu, Maharajan Chandrasekaran, and Michael M. Aruldhas -- 11. Novel Coordination Complexes of a Few Essential Trace Metals: Cytotoxic Properties and Lead Identification for Drug Development for Cancer / Anvarbatcha Riyasdeen, Rangasamy Loganathan, Mallayan Palaniandavar, and Mohammed A. Akbarsha -- 12. Why Is Gallbladder Cancer Common in Gangetic Belt? / Ruhi Dixit and V.K. Shukla -- 13. Stress and Cancer Risk: The Possible Role of Work Stress / Marcus James Fila.

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