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Immunobiology of the complement system : an introduction for research and clinical medicine /

Immunobiology of the Complement System: An Introduction for Research and Clinical Medicine provides an introduction to the complement system. The intention was to create a primer that would provide the basic knowledge of complement required for either research or clinical medicine in diseases involv...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Ross, Gordon D.
Published: Academic Press,
Publisher Address: Orlando :
Publication Dates: [1986]
Literature type: eBook
Language: English
Subjects:
Complement (Immunology)
Complement activation.
Complement System Proteins > immunology.
HEALTH & FITNESS > General. > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Man > Blood plasma > Complement
Electronic books.
Online Access: http://www.sciencedirect.com/science/book/9780125976404
Summary: Immunobiology of the Complement System: An Introduction for Research and Clinical Medicine provides an introduction to the complement system. The intention was to create a primer that would provide the basic knowledge of complement required for either research or clinical medicine in diseases involving the complement system.
Carrier Form: 1 online resource (xi, 273 pages) : illustrations
Bibliography: Includes bibliographical references and index.
ISBN: 9781483276397
1483276392
Index Number: QR185
CLC: R371
Contents: Front Cover; Immunobiology of the Complement System: An Introduction for Research and Clinical Medicine; Copyright Page; Table of Contents; Preface; Introduction and History of Complement Research; I. THE COMPLEMENT SYSTEM; II. HISTORY OF RESEARCH ON COMPLEMENT; III. ROLE OF COMPLEMENT IN INFECTIONS ANDAUTOIMMUNE DISEASE; REFERENCES OF HISTORICAL INTEREST; Chapter 1. The Classical Pathway; I. INTRODUCTION; II. ACTIVATION CASCADE; III. REGULATORY FACTORS; IV. SUMMARY OF AMPLIFICATION FACTORS; REFERENCES; Chapter 2. The Alternative Pathway; I. INTRODUCTION; II. THE PROTEINS.
III. THE ACTIVATION PROCESSIV. REGULATION OF ALTERNATIVE PATHWAYACTIVATION BY MEMBRANE-ASSOCIATED PROTEINS; V. BIOLOGICAL EFFECTS OF ALTERNATIVEPATHWAY ACTIVATION; REFERENCES; Chapter 3. Complement Mediatorsof Inflammation; I. INTRODUCTION; II. PRODUCTION OF THE ANAPHYLATOXINS; III. CONTROL MECHANISMS; IV. PHYSIOCHEMICAL CHARACTERIZATION OF THEHUMAN ANAPHYLATOXINS; V. BIOLOGICAL ACTIVITIES OF THE ANAPHYLATOXI NS; VI. THE C5a RECEPTOR; VII. SUMMARY; REFERENCES; Chapter 4. Opsonization and MembraneComplement Receptors; I. INTRODUCTION; II. OPSONIZATION; III. MEMBRANE COMPLEMENT RECEPTORS.
IV. METHODS FOR DIRECTION OF OPSONIC COMPLEMENT FRAGMENTS AND COMPLEMENTRECEPTORSREFERENCES; Chapter 5. Assembly and Functions of theTerminal Components; I. INTRODUCTION; II. ASSEMBLY OF THE MAC; III. FUNCTIONAL EFFECTS OF THE MACON TARGET MEMBRANES; IV. ESCAPE MECHANISMS FROM MAC ATTACK; V. PATHOPHYSIOLOGICAL SIGNIFICANCE OF THEMEMBRANE ATTACK SEQUENCE; VI. PROTECTION OF HOST CELLS FROM ATTACKBY MAC; VII. PERSPECTIVES; ACKNOWLEDGMENTS; REFERENCES; Chapter 6.Complement-Dependent Mechanisms of Virus Neutralization; I. INTRODUCTION; II. IMMUNITY TO VIRUSES AND VIRUS-INFECTED CELLS.
III. COMPLEMENT ACTIVATION BY VIRUSES ANDVIRUS-INFECTED CELLSIV. ANTIBODY- AND COMPLEMENT-DEPENDENT VIRALNEUTRALIZATION; V. EFFECTS OF ANTIBODY AND COMPLEMENT ONVIRUS-INFECTED CELLS; VI. CONCLUSIONS; REFERENCES; Chapter 7. Genetics and Synthesis of Components of the ComplementSystem; I. INTRODUCTION; II. GENETIC VARIANTS: POLYMORPHISM OF THECOMPLEMENT PROTEINS; III. STRUCTURE AND ORGANIZATION OFCOMPLEMENT GENES; IV. EXPRESSION OF COMPLEMENT GENES; V. COMPLEMENT DEFICIENCIES; VI. CONCLUSIONS; REFERENCES; Chapter 8. Role of Complement inInfectious Diseases; I. INTRODUCTION.
II. MICROBIAL ANTIGENS CAPABLEOF ACTIVATING COMPLEMENTIII. LOCALIZATION OF ANTIBODY AND COMPLEMENTCOMPONENTS ON MICROORGANISMS; IV. COMPLEMENT-MEDIATED LYSIS OF BACTERIA; V. ROLE OF ANTIBODY AND COMPLEMENT IN BLOODSTREAMCLEARANCE OF MICROORGANISMS; VI. NONCOMPLEMENT AND NONANTIBODY FACTORSINTERACTING WITH COMPLEMENT IN HOST DEFENSE; VII. ROLE OF COMPLEMENT IN THE PATHOGENESISOF INFECTIOUS DISEASE; VIII. CONCLUSIONS; REFERENCES; Chapter 9. Complement and theRheumatic Diseases; I. INTRODUCTION; II. SYSTEMIC LUPUS ERYTHEMATOSUS; III. RHEUMATOID ARTHRITIS ANDRELATED ARTHRITIDES; IV. CRYOGLOBULINS.

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