Pharmacology of G protein coupled receptors
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Group Author: | |
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Published: |
Elsevier Academic Press,
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Publisher Address: | Amsterdam Boston |
Publication Dates: | 2011. |
Literature type: | Book |
Language: | English |
Series: |
Advances in pharmacology ; v. 62 |
Subjects: | |
Carrier Form: | xvi, 391 p.: ill. ; 24 cm. |
ISBN: |
9780123859525 (hbk.) 0123859522 (hbk.) |
Index Number: | Q513 |
CLC: | Q513 |
Call Number: | Q513/P536 |
Contents: |
Includes bibliographical references and index. Use of GPCR structures in drug design -- Allosteric modulation of metabotropic glutamate receptors -- Refining efficacy: exploiting functional selectivity for drug discovery -- Pharmacological chaperones for misfolded gonadotropin-releasing hormone receptors -- Regulation of stability and trafficking of calcium-sensing receptors by pharmacologic chaperones -- Experimental challenges to targeting poorly characterized GPCRs: uncovering the therapeutic potential for free fatty acid receptors -- Biological and pharmacological roles of HCA receptors -- Pharmacology, signaling and physiological relevance of the G protein-coupled receptor 55 -- Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity -- Regulator of G protein signaling proteins as drug targets: current state and future possibilities -- GPCR-interacting proteins, major players of GPCR function. |