Pharmacology of G protein coupled receptors

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Bibliographic Details
Group Author: Neubig Richard R.
Published: Elsevier Academic Press,
Publisher Address: Amsterdam Boston
Publication Dates: 2011.
Literature type: Book
Language: English
Series: Advances in pharmacology ; v. 62
Subjects:
Carrier Form: xvi, 391 p.: ill. ; 24 cm.
ISBN: 9780123859525 (hbk.)
0123859522 (hbk.)
Index Number: Q513
CLC: Q513
Call Number: Q513/P536
Contents: Includes bibliographical references and index.
Use of GPCR structures in drug design -- Allosteric modulation of metabotropic glutamate receptors -- Refining efficacy: exploiting functional selectivity for drug discovery -- Pharmacological chaperones for misfolded gonadotropin-releasing hormone receptors -- Regulation of stability and trafficking of calcium-sensing receptors by pharmacologic chaperones -- Experimental challenges to targeting poorly characterized GPCRs: uncovering the therapeutic potential for free fatty acid receptors -- Biological and pharmacological roles of HCA receptors -- Pharmacology, signaling and physiological relevance of the G protein-coupled receptor 55 -- Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity -- Regulator of G protein signaling proteins as drug targets: current state and future possibilities -- GPCR-interacting proteins, major players of GPCR function.