Biocatalysis for the pharmaceutical industry discovery, development, and manufacturing /
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Main Authors: | |
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Group Author: | ; |
Published: |
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Literature type: | Electronic eBook |
Language: | English |
Subjects: | |
Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9780470823163 |
Carrier Form: | 1 online resource (x, 324 p.) : ill. |
Bibliography: | Includes bibliographical references and index. |
ISBN: |
9780470823156 (electronic bk.) 0470823151 (electronic bk.) |
Index Number: | RS380 |
CLC: | R914 |
Contents: | Enzymes and their synthetic applications -- Expression hosts for enzyme discovery and production -- Directed enzyme evolution and high-throughput screening -- Applications of reaction engineering to industrial biotransformations -- Chiral synthesis of pharmaceutical intermediates using oxynitrilases -- Expanding the scope of aldolases as tools for organic synthesis -- Synthetic applications of ketoreductases and alcohol oxidases -- Applications of nitrile hydratases and nitrilases -- Biosynthesis of drug metabolites -- Application of whole-cell biotransformation in the pharmaceutical industry -- Combinatorial biosynthesis of pharmaceutical natural products -- Metabolitic engineering for the development and manufacturing of pharmaceuticals -- Multimodular synthases and supporting enzymes for chemical production -- Green chemistry with biocatalysis for production of pharmaceuticals. |