Screen LibraryGenome instability : methods and protocols /
This volume presents forty-two methods and protocols to analyze diverse aspects of genome instability. Chapters detail mutagenesis and repair, methods to quantify and analyze the properties of DNA double-strand breaks, profile replication, replication proteins strand-specifically, genome instability...
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| Group Author: | ; |
|---|---|
| Published: |
Humana Press,
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| Publisher Address: | New York, NY : |
| Publication Dates: | [2018] |
| Literature type: | Book |
| Language: | English |
| Series: |
Methods in molecular biology,
1672 Springer protocols |
| Subjects: | |
| Summary: |
This volume presents forty-two methods and protocols to analyze diverse aspects of genome instability. Chapters detail mutagenesis and repair, methods to quantify and analyze the properties of DNA double-strand breaks, profile replication, replication proteins strand-specifically, genome instability, fluorescence microscopic techniques, and genomic and proteomic approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible lab |
| Carrier Form: | xvi, 663 pages : illustrations (some color), forms ; 27 cm. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9781493973057 (hardback) : 1493973053 (hardback) 9781493973064 (eBook) 1493973061 (eBook) |
| Index Number: | QH440 |
| CLC: | Q343.1-33 |
| Call Number: | Q343.1-33/G335 |
| Contents: |
A-like faker assay for measuring yeast chromosome III stability / Chromosome transmission fidelity assay for measuring chromosome loss in yeast / Measuring mutation rates using the luria-delbruck fluctuation assay / Molecular genetic characterization of mutagenesis using a highly sensitive single-stranded DNA reporter system in budding yeast / Analyzing genome rearrangements in Saccharomyces cerevisiae / |