From genome to therapy integrating new technologies with drug development /
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Corporate Authors: | ; |
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Group Author: | ; ; |
Published: |
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Literature type: | eBook |
Language: | English |
Series: |
Novartis Foundation symposium ; 229. |
Subjects: | |
Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/047084664X |
Item Description: | "Symposium on From Genome to Therapy: Integrating New Technologies with Drug Development, held at the Hotel Europe, Basel, Switzerland, 22-24 June 1999"--Contents page. |
Carrier Form: | 1 online resource (viii, 165 pages) : illustrations. |
Bibliography: | Includes bibliographical references and index. |
ISBN: |
047085183X 9780470851838 0471627445 9780471627449 047084664X 9780470846643 |
Index Number: | RM301 |
CLC: | R968-532 |
Contents: |
Introduction / Electrophoresis-based fluorescent dideoxy-terminator sequencing / Genomic impact on pharmaceutical development / From transcription regulation to cell cycle checkpoint / Mass spectrometry resurrects protein-based approaches in functional genomics / A clinical molecular scanner to study human proteome complexity / From proteomics to functional analysis / Microbial genome sequencing : new insights into physiology and evolution / Pharmacogenetics and pharmacogenetics in the discovery and development of medicines / Mutagensis and genomics in the mouse : towards systematic studies of mammalian gene function / Biological annotation of the Drosphila genome sequence / Applications of high-density oligonucleotide arrays / Plasmodium falciparum : from genomic sequence to vaccines and drugs / Functional analysis of the yeast genome by precise deletion and parallel phenotypic characterization / Patenting genes and gene therapy : legal and ethical aspects / Ethical issues from genome to therapy / The impact of genomics on drug discovery / From genome to therapy : industry perspective / Final general discussion. |