Cortical development genes and genetic abnormalities.

To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timely and insightful discussion between developmental neurobiologists and clinicians who deal with disord...

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Bibliographic Details
Corporate Authors: Symposium on Cortical Development: Genes and Genetic Abnormalities Novartis Foundation); Novartis Foundation.
Group Author: Bock, Gregory.; Goode, Jamie
Published:
Literature type: Electronic eBook
Language: English
Series: Novartis Foundation symposium ; 288
Subjects:
Online Access: http://onlinelibrary.wiley.com/book/10.1002/9780470994030
Summary: To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timely and insightful discussion between developmental neurobiologists and clinicians who deal with disorders of the nervous system. Chapters in this book deal specifically with cell fate determination, cell migration and disorders of cell migration; current concepts and new ideas about cortical arealisation, and disorders which can arise from incorrect arealisation; genes implicated in the development of cortical connectivity and related pathologies such as schizophrenia and synaesthesia; and susceptibility genes for cognitive disorders such as schizophrenia, autism, dyslexia, and attention deficit disorder.
Item Description: "Symposium on Cortical Development: Genes and Genetic Abnormalities, held at the Novartis Foundation, London, 6-8 February 2007"--Page v.
Editors: Gregory Bock and Jamie Goode.
Carrier Form: 1 online resource (xi, 289 pages) : illustrations.
Bibliography: Includes bibliographical references and indexes.
ISBN: 9780470994030
0470994037
9780470994023
0470994029
1281320099
9781281320094
Index Number: QP376
CLC: R338.2-532
Contents: Molecular development of corticospinal motor neuron circuitry / Bradley J. Molyneaux, Paola Arlotta and Jeffrey D. Macklis -- Perspectives on the developmental origins of cortical interneuron diversity / Gordon Fishell -- Genetic determinants of neuronal migration in the cerebral cortex / Pasko Rakic, Kazue Hashimoto-Torii and Matthew R. Sarkisian -- Neural stem and progenitor cells in cortical development / Stephen C. Noctor, Veronica Martinez-Cerdeño and Arnold R. Kriegstein -- Genes that control the size of the cerebral cortex / Teresa H. Chae and Christopher A. Walsh -- Control of cortical neuron layering : lessons from mouse chimeras / Vicki Hammond, Joanne Britto, Eva So, Holly Cate and Seong-Seng Tan -- Intracortical multidirectional migration of cortical interneurons / Fujio Murakami, Daisuke Tanaka, Mitsutoshi Yanagida and Emi Yamazaki -- The atypical cadherin Celsr3 regulates the development of the axonal blueprint / Libing Zhou, Fadel Tissir and André M. Goffinet -- Regulation of laminar and area patterning of mammalian neocortex and behavioural implications / Dennis D.M. O'Leary, Shen-Ju Chou, Tadashi Hamasaki, Setsuko Sahara, Akihide Takeuchi, Sandrine Thuret and Axel Leingärtner -- Genetic regulation of prefrontal cortex development and function / Jeremy A. Cholfin and John L.R. Rubenstein -- Self-organization and pattern formation in primate cortical networks / Henry Kennedy, Rodney Douglas, Kenneth Knoblauch and Colette Dehay -- Molecular mechanisms of thalamocortical axon targeting / Nobuhiko Yamamoto, Takuro Maruyama, Naofumi Uesaka, Yasufumi Hayano, Makoto Takemoto and Akito Yamada -- Genes involved in the formation of the earliest cortical circuits / Zoltán Molnár, Anna Hoerder-Suabedissen, Wei Zhi Wang, Jamin DeProto, Kay Davies, Sheena Lee, Erin C. Jacobs, Anthony T. Campagnoni, Ole Paulsen, Maria Carmen Piñon and Amanda F.P. Cheung -- Emx and Nfi genes regulate cortical development and axon guidance in the telencephalon / Michael Piper, Amber-Lee S. Dawson, Charlotta Lindwall, Guy Barry, Céline Plachez and Linda J. Richards -- Schizophrenia susceptibility genes and their neurodevelopmental implications: focus on neuregulin 1 / Paul J. Harrison -- Focal brain malformations : a spectrum of disorders along the mTOR cascade / Peter B. Crino.