Quantum pharmacology /
Saved in:
Main Authors: | |
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Corporate Authors: | |
Published: |
Butterworths,
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Publisher Address: | London ; Boston : |
Publication Dates: | 1983. |
Literature type: | eBook |
Language: | English |
Edition: | Second edition. |
Subjects: | |
Online Access: |
http://www.sciencedirect.com/science/book/9780408709507 |
Carrier Form: | 1 online resource (xiv, 273 pages) : illustrations |
Bibliography: | Includes bibliographical references (pages 243-268) and index. |
ISBN: |
9781483163673 1483163679 |
Index Number: | RM301 |
CLC: | R912 |
Contents: |
Front Cover; Quantum Pharmacology; Copyright Page; Preface to second edition; Preface to first edition; Table of Contents; Introduction; Part I: Molecular pharmacology; Chapter 1. Small molecules in biology; Action Potentials; The classification of nerves; Neuron structure and junctions; Nerve transmitters; Synaptic actions of neuro-transmitters; Receptors; Summary; Further reading; Chapter 2. Quantitative pharmacology; Pharmacological measurements; Responses; Dose-response curves; Direct binding studies; Theories of drug action; Quantitative receptor theory; Some complications; Summary. Physiological and pathological effectsHistamine release; Pharmacological testing; Agonists; H1 Antagonists; H2 Antagonists; Summary; Further reading; Chapter 6. Central nervous system I. Monoamines and acetylcholine; Chemical transmitters; Catecholamines; Histamine; Acetylcholine; Central nervous system drugs; Antipsychotics; Antidepressants; Psychomotor stimulants; Hallucinogens; Further reading; Chapter 7. Central nervous system II. Amino acids and peptides; Amino acids; Anti-anxiety drugs; Anti-epileptic drugs; Peptides; Analgesics; Summary; Further reading; Chapter 8. Anaesthetics. General anaestheticsTheories of general anaesthesia; Local anaesthetics; Summary; Further reading; Chapter 9. Chemotherapy; Sulphonamides; Antibiotics; Antimalarials; Antiviral agents; Cancer chemotherapy; Summary; Further reading; Chapter 10. Other areas; Kinins; Prostaglandins; Anti-inflammatory drugs; Hormones; Vitamins; Summary; Further reading; Part II: Molecular quantum mechanics; Chapter 11. Wave functions and orbitals; Wave functions; Orbitals; Spin-orbitals and antisymmetry; Molecular orbitals; Secular equations; Matrix elements; Self-consistent molecular orbitals. Configuration interactionSummary; Further reading; Chapter 12. Approximate wave functions; Ab initio methods; Correlation energy; Semi-empirical calculations; Neglect of differential overlap; The use of localized orbitals; Use of an undefined hamiltonian operator; Computer programs for molecular orbital calculations; Summary; Further reading; Chapter 13. Calculated molecular properties; Energies; Molecular geometry; Conformation; Conformational free energies; Ionization potentials and electron affinities; Charge distribution; Mulliken population analysis; Molecular potential fields. |