Screen LibraryProtein kinase inhibitors in research and medicine /
Saved in:
| Group Author: | |
|---|---|
| Published: |
Elsevier/Academic Press,
|
| Publisher Address: | Amsterdam : |
| Publication Dates: | 2014. |
| Literature type: | Book |
| Language: | English |
| Edition: | First edition. |
| Series: |
Methods in enzymology,
volume 548 |
| Subjects: | |
| Carrier Form: | xii, 241, 42 unnumbered pages of plates : illustrations (some color) ; 24 cm. |
| Bibliography: | Includes bibliographical references and indexes. |
| ISBN: |
9780123979186 0123979188 |
| Index Number: | QP606 |
| CLC: | Q556 |
| Call Number: | Q556/P967 |
| Contents: |
Catalytic mechanisms and regulation of protein kinases / A structural atlas of kinases inhibited by clinically approved drugs / Fragment-based approaches to the discovery of kinase inhibitors / Targeting protein kinases with selective and semipromiscuous covalent inhibitors / The resistance tetrad : amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles / FLiK : a direct-binding assay for the identification and kinetic characterization of stabilizers of inactive kinase conformations / Discovery of allosteric Bcr-Abl inhibitors from phenotypic screen to clinical candidate / The logic and design of analog-sensitive kinases and their small molecule inhibitors / |