The theory of response-adaptive randomization in clinical trials
Presents a firm mathematical basis for the use of response-adaptive randomization procedures in practiceThe Theory of Response-Adaptive Randomization in Clinical Trials is the result of the authors' ten-year collaboration as well as their collaborations with other researchers in investigating t...
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Literature type: | Electronic eBook |
Language: | English |
Series: |
Wiley series in probability and statistics
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Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/047005588X |
Summary: |
Presents a firm mathematical basis for the use of response-adaptive randomization procedures in practiceThe Theory of Response-Adaptive Randomization in Clinical Trials is the result of the authors' ten-year collaboration as well as their collaborations with other researchers in investigating the important questions regarding response-adaptive randomization in a rigorous mathematical framework. |
Carrier Form: | xiii, 218 pages : illustrations ; 25 cm. |
Bibliography: | Includes bibliographical references and indexes. |
ISBN: |
047005588X 9780470055885 0470055871 9780470055878 |
Index Number: | R853 |
CLC: | R446 |
Contents: | Fundamental questions of response-adaptive randomization -- Likelihood-based inference -- Procedures based on urn models -- Procedures based on sequential estimation -- Sample size calculation -- Additional considerations -- Implications for the practice of clinical trials -- Incorporating covariates -- Conclusions and open problems. |