Molecular recognition of DNA double helix : gene regulation and photochemistry of BrU substituted DNA ; development of chemical biology tools /
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Main Authors: | |
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Published: |
Springer,
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Publisher Address: | Singapore : |
Publication Dates: | [2018] |
Literature type: | Book |
Language: | English |
Series: |
Springer theses,
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Subjects: | |
Item Description: | "Doctoral thesis accepted by Kyoto University, Kyoto, Japan." |
Carrier Form: | xvi, 114 pages : illustrations (some color) ; 25 cm. |
Bibliography: | Includes bibliographical references. |
ISBN: |
9789811087455 9811087458 |
Index Number: | QP624 |
CLC: | Q523 |
Call Number: | Q523/S131 |
Contents: | 1. Overview of DNA minor groove binding synthetic small molecules and photochemistry of BrU substituted DNA -- 2. Synthesis and Biological Evaluation of Targeted Transcriptional Activator with HDAC8 Inhibitory Activity -- 3. Chemical Modification of a Synthetic Small Molecule Boosts its Biological Efficacy against Pluripotency Genes in Mouse Fibroblast -- 4. Development of a novel photochemical detection technique for the analysis of polyamide binding sites -- 5. Examining cooperative binding of Sox2 on DC5 regulatory element upon complex formation with Pax6 through excess electron transfer |