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Models of protection against HIV/SIV : avoiding AIDS in humans and monkeys /

A successful vaccine for the prevention and/or immunotherapy against HIV/AIDS is one of the prominent challenges of the 21st century. To date, all human vaccine trials against this virus/disease have resulted in failure, or at best have shown very low efficacy. The scientific community dealing with...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology
Group Author: Pancino, Gianfranco; Silvestri, Guido Professor of pathology and laboratory medicine; Fowke, Keith R
Published: Academic Press,
Publisher Address: London ; Waltham, MA :
Publication Dates: 2012.
Literature type: eBook
Language: English
Edition: First edition.
Subjects:
HIV infections > Prevention
Vaccines > Testing
HIV Infections > immunology
HIV Infections > prevention & control
Disease Models, Animal
HIV > immunology
Simian Acquired Immunodeficiency Syndrome > immunology
Electronic books
Online Access: http://www.sciencedirect.com/science/book/9780123877154
Summary: A successful vaccine for the prevention and/or immunotherapy against HIV/AIDS is one of the prominent challenges of the 21st century. To date, all human vaccine trials against this virus/disease have resulted in failure, or at best have shown very low efficacy. The scientific community dealing with HIV/AIDS has unanimously proposed a focus on basic science, with the intention of identifying correlates of protection that can serve as guides in developing and evaluating vaccine preparation. However, Nature seems to have already found several ways of dealing with infections by HIV and related p
Carrier Form: 1 online resource (xiv, 345 pages) : illustrations
Bibliography: Includes bibliographical references and index.
ISBN: 9780123877161
0123877164
Index Number: RA644
CLC: R512.91
Contents: Simian models of non-pathogenic -- SIV infection -- Natural SIV infection: virological aspects -- Natural SIV infection: immunological aspects -- Prevention Implications for therapy HIV-1-exposed seronegative individuals -- Are some people protected against HIV infection? -- The genital mucosa, the front lines in the defense against HIV -- Host genetics and resistance to HIV-1 infection -- The immune system and resisting HIV infection -- HIV-1-controllers -- Definition, natural history and heterogeneity of HIV-controllers -- Residual viremia and viral reservoirs in elite controllers Immune r

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