Guide to research techniques in neuroscience /

Neuroscience is, by definition, a multidisciplinary field: some scientists study genes and proteins at the molecular level while others study neural circuitry using electrophysiology and high-resolution optics. A single topic can be studied using techniques from genetics, imaging, biochemistry, or e...

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Bibliographic Details
Main Authors: Carter, Matt, 1978
Corporate Authors: Elsevier Science & Technology
Group Author: Jennifer Shieh; Farra, Natalie; Harris, Greg
Published: Academic Press,
Publisher Address: Amsterdam [Netherlands] :
Publication Dates: 2015.
©2015
Literature type: eBook
Language: English
Edition: Second edition.
Subjects:
Online Access: http://www.sciencedirect.com/science/book/9780128005118
Summary: Neuroscience is, by definition, a multidisciplinary field: some scientists study genes and proteins at the molecular level while others study neural circuitry using electrophysiology and high-resolution optics. A single topic can be studied using techniques from genetics, imaging, biochemistry, or electrophysiology. Therefore, it can be daunting for young scientists or anyone new to neuroscience to learn how to read the primary literature and develop their own experiments. This volume addresses that gap, gathering multidisciplinary knowledge and providing tools for understanding the neurosc.
Carrier Form: 1 online resource (417 pages) : illustrations, photographs
Bibliography: Includes bibliographical references at the end of each chapters and index.
ISBN: 9780128005972
0128005971
Index Number: RC337
CLC: R741
Contents: Front Cover; Guide to Research Techniques in Neuroscience; Copyright; Contents; Foreword to the Second Edition; Foreword to the First Edition; Preface to the Second Edition; Preface to the First Edition; Introduction; LEVELS OF INVESTIGATION; METHODS OF STUDYING THE NERVOUS SYSTEM; UNDERSTANDING TECHNIQUES IN NEUROSCIENCE; Chapter 1 -- Whole-Brain Imaging; STRUCTURAL BRAIN IMAGING TECHNIQUES; FUNCTIONAL BRAIN IMAGING TECHNIQUES; FUNCTIONAL IMAGING EXPERIMENTAL DESIGN AND ANALYSIS; CONCLUSION; SUGGESTED READING AND REFERENCES; Books; Review Articles.
Primary Research Articles-Interesting Examples from the LiteratureProtocols; Websites; Chapter 2 -- Animal Behavior; CONSIDERATIONS FOR CHOOSING AND PERFORMING A BEHAVIORAL ASSAY; RODENT BEHAVIORAL PARADIGMS; DROSOPHILA BEHAVIORAL PARADIGMS; CAENORHABDITIS ELEGANS BEHAVIORAL PARADIGMS; NONHUMAN PRIMATE BEHAVIORAL PARADIGMS; CONCLUSION; SUGGESTED READING AND REFERENCES; Books and Review Articles; Primary Research Articles-Papers First Describing Standard Behavioral Assays; Primary Research Articles-Interesting Examples from the Literature; Protocols.
Chapter 3 -- Stereotaxic Surgeries and In Vivo TechniquesSTEREOTAXIC SURGERIES; IMPLANTS FOR LONG-TERM ACCESS TO THE BRAIN; MANIPULATING NEURAL ACTIVITY IN VIVO; CONCLUSION; SUGGESTED READING AND REFERENCES; Books; Review Articles; Primary Research Articles-Interesting Examples from the Literature; Protocols; Chapter 4 -- Electrophysiology; A BRIEF REVIEW OF THE ELECTRICAL PROPERTIES OF NEURONS; THE ELECTROPHYSIOLOGY RIG; CATEGORIES OF ELECTROPHYSIOLOGY RECORDINGS; ELECTROPHYSIOLOGY TISSUE PREPARATIONS; MANIPULATING NEURAL ACTIVITY DURING ELECTROPHYSIOLOGY EXPERIMENTS; CONCLUSION.
SUGGESTED READING AND REFERENCESBooks; Review Articles; Primary Research Articles-Interesting Examples from the Literature; Protocols; Chapter 5 -- Microscopy; ESSENTIAL PRINCIPLES OF MICROSCOPY; LIGHT MICROSCOPY; FLUORESCENCE MICROSCOPY; ELECTRON MICROSCOPY; PREPARING AND INTERPRETING MICROSCOPY DATA; CONCLUSION; SUGGESTED READING AND REFERENCES; Books; Review Articles; Primary Research Articles-Interesting Examples from the Literature; Protocols; Websites; Chapter 6 -- Visualizing Neural Structure; TISSUE PREPARATION; VISUALIZING MORPHOLOGY; VISUALIZING GENE AND PROTEIN EXPRESSION.
VISUALIZING CIRCUITRYCONCLUSION; SUGGESTED READING AND REFERENCES; Books; Review Articles; Primary Research Articles-Interesting Examples from the Literature; Protocols; Websites; Chapter 7 -- Visualizing Neural Function; STATIC MARKERS OF ACTIVITY; VISUALIZING NEURAL ACTIVITY; VISUALIZING PROTEIN FUNCTION; CONCLUSION; SUGGESTED READING AND REFERENCES; Books; Review Articles; Primary Research Articles-Interesting Examples from the Literature; Protocols; Chapter 8 -- Manipulating Neural Activity; EXPERIMENTAL LOGIC OF MANIPULATING NEURAL ACTIVITY; PHYSICAL MANIPULATION; ELECTRICAL MANIPULATIO