Approaches to the conformational analysis of biopharmaceuticals

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Bibliographic Details
Main Authors: Lundblad Roger L
Published: CRC Press,
Publisher Address: Boca Raton
Publication Dates: c2010.
Literature type: Book
Language: English
Series: Protein science series
Subjects:
Carrier Form: xiii, 354 p.: ill. ; 25 cm.
ISBN: 9781439807804 (hardcover : alk. paper)
1439807809 (hardcover : alk. paper)
Index Number: R977
CLC: R977.6
Call Number: R977.6/R962
Contents: Includes bibliographical references and index.
Introduction to biopharmaceutical conformational analysis : issues and methods -- Comparability of biotechnological/biological products and biological generics -- Application of native electrophoresis for the study of protein conformation -- Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation -- Size-exclusion chromatography and bimolecular conformation -- Use of analytical ultracentrifugation to study biomolecular conformation -- Use of differential scanning calorimetry to measure conformational change in proteins and other biomac