Incorporation of Heterocycles into Combinatorial Chemistry /
The author has summarized a decade of teaching combinatorial chemistry into this timely brief. The solid phase synthesis of unnatural heterocyclic alpha-amino acids is illustrated by practical examples starting from the ABCs of peptide synthesis explored in chapter one. Chapter two is concerned with...
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Main Authors: | |
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Published: |
Springer International Publishing : Imprint: Springer,
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Publisher Address: | Cham : |
Publication Dates: | 2017. |
Literature type: | eBook |
Language: | English |
Series: |
SpringerBriefs in Molecular Science,
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Subjects: | |
Online Access: |
http://dx.doi.org/10.1007/978-3-319-50015-7 |
Summary: |
The author has summarized a decade of teaching combinatorial chemistry into this timely brief. The solid phase synthesis of unnatural heterocyclic alpha-amino acids is illustrated by practical examples starting from the ABCs of peptide synthesis explored in chapter one. Chapter two is concerned with the solid phase synthesis which is shown on various techniques BillBoard, tea-bag, and Lantern devices, and demonstrated on heterocyclic examples and protocols. In the third chapter the tools for accelerating chemical synthesis solid phase and liquid phase are reviewed. Here the techniques of par |
Carrier Form: | 1 online resource (XI, 117 pages) : illustrations. |
ISBN: | 9783319500157 |
Index Number: | QD415 |
CLC: | O62 |
Contents: | Introduction -- Peptide Synthesis of Libraries of Non-Natural Amino Acids -- The choice of tools for implementing multi-stage transformations. SPOS for Beginners -- Secrets of Parallel Liquid-Phase Synthesis -- Most Combinatorial LPOS Reactions: Reductive Amination with a Scavenger -- A Parallel Ugi Reaction -- Combinatorial Heterocyclic Chemistry in Higher School. |