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Lead generation approaches in drug discovery

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Bibliographic Details
Group Author: Rankovic Zoran.; Morphy Richard.
Published: John Wiley,
Publisher Address: Hoboken, N.J.
Publication Dates: c2010.
Literature type: Book
Language: English
Subjects:
Drug development.
Drugs > Design.
High throughput screening (Drug development)
Drug Discovery > methods.
Lead.
Carrier Form: xi, 295 p.: ill. ; 25 cm.
ISBN: 9780470257616 (cloth)
047025761X (cloth)
Index Number: R914
CLC: R914.2
Call Number: R914.2/L434
Contents: Includes bibliographical references and index.
Lead discovery : the process / William F. Michne -- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy -- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath -- Fragment-based lead discovery / Jeffrey S. Albert -- Design of multitarget ligands / Richard Morphy and Zoran Rankovic -- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak -- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann -- Early screening for ADMET properties / Dennis A. Smith -- Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm.

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