Lead generation approaches in drug discovery
Saved in:
Group Author: | ; |
---|---|
Published: |
John Wiley,
|
Publisher Address: | Hoboken, N.J. |
Publication Dates: | c2010. |
Literature type: | Book |
Language: | English |
Subjects: | |
Carrier Form: | xi, 295 p.: ill. ; 25 cm. |
ISBN: |
9780470257616 (cloth) 047025761X (cloth) |
Index Number: | R914 |
CLC: | R914.2 |
Call Number: | R914.2/L434 |
Contents: |
Includes bibliographical references and index. Lead discovery : the process / William F. Michne -- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy -- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath -- Fragment-based lead discovery / Jeffrey S. Albert -- Design of multitarget ligands / Richard Morphy and Zoran Rankovic -- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak -- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann -- Early screening for ADMET properties / Dennis A. Smith -- Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm. |