Screen LibraryThe biology of exercise /
"Exercise training provokes widespread transformations in the human body, requiring coordinated changes in muscle composition, blood flow, neuronal and hormonal signaling, and metabolism. These changes enhance physical performance, improve mental health, and delay the onset of aging and disease...
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| Group Author: | ; ; |
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| Published: |
Cold Spring Harbor Laboratory Press,
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| Publisher Address: | Cold Spring Harbor, New York : |
| Publication Dates: | [2017] |
| Literature type: | Book |
| Language: | English |
| Series: |
Cold Spring Harbor perspectives in medicine
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| Subjects: | |
| Summary: |
"Exercise training provokes widespread transformations in the human body, requiring coordinated changes in muscle composition, blood flow, neuronal and hormonal signaling, and metabolism. These changes enhance physical performance, improve mental health, and delay the onset of aging and disease. Understanding the molecular basis of these changes is therefore important for optimizing athletic ability and for developing drugs that elicit therapeutic effects. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines the biological basis of exercise from the molecular to the systemic levels. Contributors discuss how transcriptional regulation, cytokine and hormonal signaling, glucose metabolism, epigenetic modifications, microRNA profiles, and mitochondrial and ribosomal functions are altered in response to exercise training, leading to improved skeletal muscle, hippocampal, and cardiovascular function. Cross talk among the pathways underlying tissue-specific and systemic responses to exercise is also considered. The authors also discuss how the understanding of such molecular mechanisms may lead to the development of drugs that mitigate aging and disease. This volume will therefore serve as a vital reference for all involved in the fields of sports science and medicine, as well as anyone seeking to understand the molecular mechanisms by which exercise promotes whole-body health."--Page 4 of cover. |
| Carrier Form: | vii, 395 pages : illustrations (chiefly color), forms ; 26 cm. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9781621822851 1621822850 9781621821656 162182165X |
| Index Number: | QP303 |
| CLC: | G804.2 |
| Call Number: | G804.2/B615-3 |
| Contents: |
Physiological Redundancy and the Integrative Responses to Exercise / The Bioenergetics of Exercise / Health Benefits of Exercise / Theoretical and Biologic Evaluation of the Link Between Low Exercise Capacity and Disease Risk / Exercise Metabolism : Fuels for the Fire / Molecular Basis of Exercise-Induced Skeletal Muscle Mitochondrial Biogenesis : Historical Advances, Current Knowledge and Future Challenges / Rate Coding and the Control of Muscle Force / Molecular Basis for Exercise-Induced Fatigue : The Importance of Strictly Controlled Cellular Ca2+ Handling / Performance Fatigability : Mechanisms and Task Specificity / Molecular Regulation of Exercise-Induced Muscle Fiber Hypertrophy / Adaptations to Endurance and Strength Training / Autophagy-Dependent Beneficial Effects of Exercise / Effects of Exercise and Aging on Skeletal Muscle / On the Run for Hippocampal Plasticity / Skeletal Muscle as an Endocrine Organ : The Role of Myokines in Exercise Adaptations / Muscle-Adipose Tissue Cross Talk / Effects of Exercise on Vascular Function, Structure, and Health in Humans / Exosomes as Mediators of the Systemic Adaptations to Endurance Exercise / Role of Nuclear Recep |