Screen LibraryEnzyme regulation in metabolic pathways /
Enzyme Regulation in Metabolic Pathways shows the reader how to understand the roles of enzymes and their kinetic constants in intermediary metabolism. It provides a means of correlating data obtained in experimental studies to multiple possible mechanisms through which some enzyme may catalyze the...
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| Main Authors: | |
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| Published: |
Wiley Blackwell,
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| Publisher Address: | Hoboken, NJ : |
| Publication Dates: | 2017. |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Summary: |
Enzyme Regulation in Metabolic Pathways shows the reader how to understand the roles of enzymes and their kinetic constants in intermediary metabolism. It provides a means of correlating data obtained in experimental studies to multiple possible mechanisms through which some enzyme may catalyze the conversion of a substrate to a product. Although not the most appropriate means of determining some potential kinetic mechanism, quasi-equilibrium assumptions are used throughout the book, keeping the rate equation derivations simple. Actual metabolic pathways with known (presumed) positive and ne |
| Item Description: | Includes index. |
| Carrier Form: | ix, 173 pages, 4 unnumbered pages of plates : illustrations (some color) ; 25 cm |
| ISBN: |
9781119155386 111915538X |
| Index Number: | QP601 |
| CLC: | Q55 |
| Call Number: | Q55/W859 |
| Contents: | Part I -- Characteristics of enzymes -- Self-assembly of polymers -- Beginnings of equations -- Metabolite distribution systems -- Modification of enzymatic activity -- Modification of metabolite flow through metabolic pathways -- Which is the real substrate? -- Non-quasi-equilibrium assumptions -- Underlying attributes of assessing enzymatic activities -- Part II -- Breakdown of the Michaelis-Menten Equation (or complex enzyme mechanisms) -- Rate equation derivation by the King-Altman Method : two substrates and two products -- Modification of enzyme mechanisms : the next generation -- What |