Screen LibrarySuccessful drug discovery /
The first volume of the book series "Successful Drug Discovery" is focusing on new drug discoveries during the last decade, from established drugs to recently introduced drugs of all kinds:small-molecule-, peptide-, and protein-based drugs.The role of serendipity is analyzed in some very s...
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| Group Author: | ; |
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| Published: |
Wiley-VCH,
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| Publisher Address: | Weinheim, Germany : |
| Publication Dates: | 2015. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9783527678433 |
| Summary: |
The first volume of the book series "Successful Drug Discovery" is focusing on new drug discoveries during the last decade, from established drugs to recently introduced drugs of all kinds:small-molecule-, peptide-, and protein-based drugs.The role of serendipity is analyzed in some very successful drugs where the research targets of the lead molecule and the drug are different. Phenotypic and target-based drug discovery approaches are discussed from the viewpoint of pioneer drugs and analogues.This volume gives an excellent overview of insulin analogues including a discussion of the propert |
| Carrier Form: | 1 online resource |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9783527678433 3527678433 1322949557 (ebk) 9781322949550 (ebk) 9783527678457 (electronic bk.) 352767845X (electronic bk.) |
| Index Number: | RS420 |
| CLC: | R914 |
| Contents: | Part I: General Aspects. Serendipitous Target-Based Drug Discoveries / János Fischer, David P Rotella -- Drug Discoveries and Molecular Mechanism of Action / David C Swinney -- Part II: Drug Class. Insulin Analogs - Improving the Therapy of Diabetes / John M Beals -- Part III: Case Histories. The Discovery of Stendra (Avanafil) for the Treatment of Erectile Dysfunction / Koichiro Yamada, Toshiaki Sakamoto, Kenji Omori, Kohei Kikkawa -- Dapagliflozin, A Selective SGLT2 Inhibitor for Treatment of Diabetes / William N Washburn -- Elvitegravir, A New HIV-1 Integrase Inhibitor for Antiretrovira |