Screen LibraryLipases and phospholipases in drug development from biochemistry to molecular pharmacology /
Lipases and Phospholipases are key control elements in mammalian metabolism. They share many common features that set them apart from other metabolic enzyme classes, most importantly their association with biological membranes. Their potential as drug targets for the treatment of metabolic diseases...
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| Group Author: | ; |
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| Literature type: | Electronic eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/3527601910 |
| Summary: |
Lipases and Phospholipases are key control elements in mammalian metabolism. They share many common features that set them apart from other metabolic enzyme classes, most importantly their association with biological membranes. Their potential as drug targets for the treatment of metabolic diseases is widely recognized, and the first lipase inhibitor drugs have been successfully introduced. Providing drug developers with a firm foundation for lipase-centered drug design, the editors of this volume have assembled experts from different scientific disciplines to create a comprehensive handbook |
| Item Description: | Title from title screen (viewed Mar 16, 2006). |
| Carrier Form: | 1 online resource (xvii, 336 pages) : illustrations, portraits |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
3527306773 9783527306770 3527605703 9783527605705 9783527601912 3527601910 |
| Index Number: | QP609 |
| CLC: | Q556 |
| Contents: | Lipases and Phospholipases in Drug Development; Contents; Preface; List of Contributors; 1 Purification of Lipase; 2 Phospholipase A(1) Structures, Physiological and Patho-physiological Roles in Mammals; 3 Rational Design of a Liposomal Drug Delivery System Based on Biophysical Studies of Phospholipase A(2) Activity on Model Lipid Membranes; 4 Phospholipase D; 5 Sphingomyelinases and Their Interaction with Membrane Lipids; 6 Glycosyl-phosphatidylinositol Cleavage Products in Signal Transduction. |