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Drug testing in vitro：breakthroughs and trends in cell culture technology

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Bibliographic Details
Group Author: Marx Uwe.; Sandig Volker.
Published: Wiley-VCH,
Publisher Address: Weinheim
Publication Dates: c2007.
Literature type: Book
Language: English
Subjects:
Drugs > Testing.
Cell culture.
Drug Evaluation, Preclinical.
Cell Culture Techniques
Carrier Form: xix, 298 p.: ill. ; 25 cm.
ISBN: 3527314881 (alk. paper)
9783527314881 (alk. paper)
Index Number: R965
CLC: R965
Call Number: R965/D794-3
Contents: Includes bibliographical references and index.
Intelligent biomatrices and engineered tissue constructs : in-vitro models for drug discovery and toxicity testing / Philip Lazarovici, Mengyan Li, Anat Perets, Mark J. Mondrinos, Shimon Lecht, Christopher D. Koharski, Paul R. Bidez III, Christine M. Finck, Peter I. Lelkes -- An overview on bioreactor design, prototyping and process control for reproducible three-dimensional tissue culture / Ralf Pörtner, Christoph Giese -- An overview on bioelectronic and biosensoric microstructures supporting high-content screening in cell cultures / Andrea A. Robitzki, Andrée Rothermel -- Novel in-vitro exposure techniques for toxicity testing and biomonitoring of airborne contaminants / Amanda Hayes, Shahnaz Bakand, Chris Winder -- Drug screening using cell lines : cell supply, high-throughput and high-content assays / Christa Burger, Oliver Pöschke, Mirek R. Jurzak -- Cell lines and primary tissues for in-vitro evaluation of vaccine efficacy / Anthony Meager -- Designer cells derived from primary tissue and designed cell lines as a sustainable cell source for drug discovery and safety assessment / Volker Sandig, Ingo Jordan -- How human embryonic stem cell research can impact in-vitro drug screening technologies of the future / André Schrattenholz, Martina Klemm -- Availability, standardization and safety of human cells and tissues for drug screening and testing / Glyn N. Stacey, Thomas Hartung -- Ethical environment and scientific rationale towards in-vitro alternatives to animal testing: where are we going? / Horst Spielmann -- How drug development of the 21st century could benefit from human micro-organoid in-vitro technologies.

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