Screen LibraryGene activity in early development /
Gene Activity in Early Development.
Saved in:
| Main Authors: | |
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| Corporate Authors: | |
| Published: |
Elsevier Science,
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| Publisher Address: | Burlington : |
| Publication Dates: | 1968. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9781483231853 |
| Summary: |
Gene Activity in Early Development. |
| Item Description: | Chapter 3: Definitive experimental evidence for localization. |
| Carrier Form: | 1 online resource (691 pages) |
| ISBN: |
9781483261478 1483261476 |
| Index Number: | QH453 |
| CLC: | Q343 |
| Contents: |
Cover image; Title page; Table of Contents; Copyright; Dedication; preface; I: gene activity in early embryogenesis; Introduction to: gene activity in early embryogenesis; Chapter 1: The variable gene activity theory of cell differentiation; Publisher Summary; early evidence for the informational equivalence of differentiated cell genomes; altered cell fate experiments; DNA constancy and the reversibility of differentiation; failure to detect differences in the DNA sequences present in differentiated cells; direct evidence for the variable gene activity theory of differentiation. Chapter 2: The onset of genome control in embryogenesisPublisher Summary; the species hybrid experiments and their conceptual background; evidence for delayed onset of embryo genome control from echinoderm species-hybrid studies; embryo genome control in the development of species-hybrids in higher deuterostomes; interpretation of the species-hybrid experiments; development in physically enucleated embryos; "chemical enucleation": development of actinomycin-treated embryos; the timing of transcription for early genome-controlled morphogenesis. Chapter 3: Early molecular indices of differentiationPublisher Summary; protein synthesis in actinomycin-treated sea urchin embryos; the appearance of histospecific proteins; Chapter 4: RNA synthesis in the early embryo; Publisher Summary; informational and ribosomal RNA synthesis in early Xenopus embryos; the amount of the genome active in the early morphogenesis of Xenopus: RNA-DNA hybridization studies; change in the informational content of the newly synthesized embryo RNA's; informational and ribosomal RNA synthesis in the early sea urchin embryo. Change in the patterns of transcription during early echinoderm developmentpatterns of early gene activity in other deuterostomes; pattern of early gene activity in protostomes; summary of biochemical data regarding onset of various classes of RNA synthesis in the embryogenesis of diverse animals; Chapter 5: The fate and function of early informational RNA; Publisher Summary; evidence suggesting that early gene products serve as templates for early embryo proteins; evidence that early gene products are stored for later utilization; Chapter 6: Maternal template RNA; Publisher Summary. The demonstration of maternal template RNAextraction of maternal template RNA and the nature of its program; fertilization and the activation of the maternal program; II: cytoplasmic localization and the onset of differentiation; Introduction to: cytoplasmic localization and the onset of differentiation; Chapter 1: The localization phenomenon; Publisher Summary; Chapter 2: Localization and preformationism; Publisher Summary; the origins of late-nineteenth-century "neopreformationism"; neopreformationism and development in lower protostomes. |