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Pathway analysis for drug discovery computational infrastructure and applications /

This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for.

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Bibliographic Details
Corporate Authors: Wiley InterScience (Online service)
Group Author: Yuryev, Anton.
Published:
Literature type: Electronic eBook
Language: English
Series: Wiley series on technologies for the pharmaceutical industry
Subjects:
Drug development > Data processing.
DNA microarrays > Data processing.
Computational Biology.
Drug Design.
Microarray Analysis > methods.
Drug development.
MEDICAL > Drug Guides.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
MEDICAL > Pharmacology. > Pharmacology.
Electronic books.
Online Access: http://onlinelibrary.wiley.com/book/10.1002/9780470399279
Summary: This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for.
Carrier Form: 1 online resource (x, 303 pages, [16] pages of plates) : illustrations (some color).
Bibliography: Includes bibliographical references and index.
ISBN: 9780470399279
0470399279
9780470399262
0470399260
1281831263
9781281831262
Index Number: RM301
CLC: R917
Contents: Cover -- CONTENTS -- Preface -- Contributors -- 1 Introduction to Pathway Analysis -- 2 Software Infrastructure and Data Model for Pathway Analysis -- 3 Automatic Pathway Inference in Heterogeneous Biological Association Networks -- 4 Algorithmic Basis for Pathway Visualization -- 5 Pathway Analysis of High-Throughput Experimental Data -- 6 Integrative Pathway Analysis of Disease Molecular Data -- 7 Whole-Genome Expression Profiling of Papillary Serous Ovarian Cancer: Activated Pathways, Potential Targets, and Noise -- 8 Mammalian Proteome and Toxicant Network Analysis -- 9 Unraveling Mechanisms of Toxicity with the Power of Pathways: ToxWiz Tool as an Illustrative Example -- 10 Impact of Chemistry Information on Pathway Analysis -- 11 Propagation of Concentration Perturbations in Equilibrium Protein Binding Networks -- 12 An Adaptive System Model of the Yeast Glucose Sensor System -- 13 Present and Future of Pathway Analysis in Drug Discovery -- Index.

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