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Protein crystallography：a concise guide

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Bibliographic Details
Main Authors: Lattman Eaton E. (Eaton Edward), 1940-
Group Author: Loll Patrick J.; (Patrick John), 1958-
Published: Johns Hopkins University Press,
Publisher Address: Baltimore
Publication Dates: 2008.
Literature type: Book
Language: English
Subjects:
Proteins > Structure.
X-ray crystallography
Proteins > Chemistry.
Crystallography, X-Ray > methods.
Protein Conformation.
Proteomics > methods.
Eiwitten.
Kristallografie.
Carrier Form: viii, 136 p.: ill., map ; 24 cm.
ISBN: 9780801888069 (hardcover : alk. paper)
0801888069 (hardcover : alk. paper)
9780801888083 (pbk. : alk. paper)
0801888085 (pbk. : alk. paper)
Index Number: Q510
CLC: Q510.1
Call Number: Q510.1/L364
Contents: Includes bibliographical references and index.
Introduction. What is x-ray crystallography? ; A quick look at protein crystals ; Noncrystalline specimens ; Summary -- A physical understanding of diffraction. What is diffraction? ; diffraction from one-dimensional crystals ; Reconstructing images from diffraction patterns ; Summary -- diffraction from three-dimensional crystals. The electron density function in three dimensions ; Calculating the diffraction pattern from a known structure ; Summary -- Phase determination by isomorphous replacement. Measuring the phases ; MAD phasing ; Fitting models to experimental electron density maps ; Summary -- The Patterson function. Definition of the Patterson function ; Using the Patterson function to locate atoms ; Summary -- Phasing with partially known structures. Difference Fourier maps ; Molecule replacement ; Summary -- Crystallographic refinement. Refinement improves the model ; Least-squares refinement ; Summary. -- Glossary.

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