Carbohydrate-spiro-heterocycles /

This volume is devoted to compounds in which the spiro centre is part of a pyranoid or furanoid or an iminosugar ring. The chapters contributed deal with methodological peculiarities of syntheses of natural and artificial sugar derived spirocycles as well as their biological applications and other u...

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Bibliographic Details
Group Author: Somsák, László; Behr, Jean-Bernard
Published: Springer,
Publisher Address: Cham :
Publication Dates: [2019]
Literature type: Book
Language: English
Series: Topics in heterocyclic chemistry, 57
Subjects:
Summary: This volume is devoted to compounds in which the spiro centre is part of a pyranoid or furanoid or an iminosugar ring. The chapters contributed deal with methodological peculiarities of syntheses of natural and artificial sugar derived spirocycles as well as their biological applications and other utilities including marketed drugs. Carbohydrates are ubiquitous molecules in nature and participate in a vast number of biological interactions. Especially their conjugates with practically all kinds of primary and secondary metabolic small molecules (and also biomacromolecules) representing valua
Carrier Form: vii, 295 pages : illustrations (some color), forms ; 24 cm.
Bibliography: Includes bibliographical references and index.
ISBN: 9783030319410 (hardback) :
3030319415 (hardback)
9783030319427 (electronic book)
3030319423 (electronic book)
Index Number: QD400
CLC: O626
Call Number: O626/C264
Contents: Anomeric Spiro-Annulated Glycopyranosides: An Overview of Synthetic Methodologies and Biological Applications -- Cycloaddition Reactions of Sugar-Based Olefins, Nitrones and Nitrile Oxides: En Route to Saccharidic Spiroisoxazoli(di)nes -- Carbohydrate Spiro-heterocycles via Radical Chemistry -- Carbohydrate-Derived Spiroketals and Spirocyclic Lactones -- Cyanohydrins and Aminocyanides as Key Intermediates to Various Spiroheterocyclic Sugars -- Recent Advances in the Chemistry and Biology of Spirocyclic Nucleosides -- Spiroketal Phthalane C-Glycosides: Synthesis of Papulacandins and SGLT2 Inh