Screen LibraryBiomaterials for tissue engineering applications a review of the past and future trends /
"A concise overview of tissue engineering technologies and materials towards specific applications, both past and potential growth areas in this unique discipline is provided to the reader. The specific area of the biomaterial component used within the paradigm of tissue engineering is examined...
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| Group Author: | ; |
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| Published: |
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| Literature type: | Electronic eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9783527646821 |
| Summary: |
"A concise overview of tissue engineering technologies and materials towards specific applications, both past and potential growth areas in this unique discipline is provided to the reader. The specific area of the biomaterial component used within the paradigm of tissue engineering is examined in detail. This is the first work to specifically covers topics of interest with regards to the biomaterial component. The book is divided into 2 sections: general materials technology (e.g., fibrous tissue scaffolds) and applications in the engineering of specific tissues (e.g., materials for cartilage tissue engineering). Each chapter covers the fundamentals and reflects not only a review of the literature, but also addresses the future of the topic. The book is intended for an audience of researchers in both industry and academia that are interested in a concise overview regarding the biomaterials component of tissue engineering, a topic that is timely and only growing as a field."--EBL book details. |
| Carrier Form: | 1 online resource (x, 564 pages) : illustrations |
| Bibliography: | Includes bibliographical references. |
| ISBN: |
9783709103852 (electronic bk.) 3709103851 (electronic bk.) 9783527646821 (electronic bk.) 3527646825 (electronic bk.) |
| Index Number: | R857 |
| CLC: | TB383 |
| Contents: |
Fibrous Scaffolds for Tissue Engineering / Introduction / Rationale for Using Fibers as a Scaffolding Material / Favorable Structural Properties / Imitation of Extracellular Matrix / Structural and Property Versatility / Microfibrous Scaffolds / Fabrication / Biomedical Applications / Nanofibrous Scaffolds / Electrospinning Technique / Setup / Fabrication and Properties of Electrospun Nanofibrous Scaffolds / Biological Enhancement with Nanofibrous Scaffold / Biomaterials for Nanofibrous Scaffolds / Comparison Between Microfibrous and Nanofibrous Scaffolds / Nanofibrous Scaffolds for Tissue Engineering Applications / Future Directions / References / Bioelastomers in Tissue Engineering / Matrix Elasticity Impacts Cell and Tissue Function / Mechanical Stimulation Affects Cell and Tissue Development / Elastic Materials are Important Scaffold Materials for Tissue Engineering / Designing Bioelastomers for Tissue Engineering / Important Considerations in Bioelastomer Design / Current State of Bioelastomers / Recent Progress of Synthetic Bioelastomers / Polyurethanes / Other Thermoplastic Bioelastomers / Poly(glycerol sebacate) / Other Thermoset Bioelastomers / Microscale Biomaterials for Tissue Engineering / Microscale Technologies for Engineering Biomaterials and the Cell Microenvironment / Photolithography / Soft Lithography / Microfluidics / Robotic Spotting and Printing / Other Microscale Techniques / Microscale Engineering of the Cell Microenvironment / Cell Patterning and Controlling Cell[-]Cell Contacts / Controlling Tissue Microarchitecture / Cell-Soluble Factor Interactions / High Thoughput and Combinatorial Investigations of the Cell Microenvironment / High Throughput Synthesis and Screening of Cell Microenvironments / Microfluidics for High Throughput Investigations of the Cell Microenvironment / Micro and Nanotechnologies for Tissue Engineering / Creation of Micro- and Nano Features on 2D Substrates / Substrate Modification / Surface Patterning / Micro Contact Printing ([æ]CP) / Micro and Nano Fluidics / Cellular Interactions with 2D Micro and Nano Patterns / Mechanism of Cell[-]Matrix Interactions / Changes in Morphology / Effect on Migration / Cellular Proliferation / Phenotype / Nanomaterials and Synthesis / Nanofibers / Nanotubes / Functionalized Nanomaterials / Interfacing Cells with Nanomaterials / Bone Tissue Engineering / Articular Cartilage Tissue Engineering / Fibrocartilaginous Tissues (Meniscus and Intervertebral Disc) / Tendon/Ligament Tissue Engineering / Neural and Muscular Tissue Engineering / Bioceramics in Tissue Engineering / Classification of Bioceramics / Bioinert Ceramics / Glass-Ceramic and Bioactive Glass / Calcium Phosphate Bioceramics / Applications of Calcium Phosphate Ceramics / Bioactive Cement / Porous Bioceramic Scaffolds for Bone Tissue Engineering / Ceramic-Based Composite Scaffold for Tissue Engineering and Drug Delivery / Bioceramics for Cancer Therapy / Bioceramics for Radiation Therapy / Bioceramics for Hyperthermia Therapy for Cancer / Bioceramics for Dental Application / Future Trends / Natural Materials in Tissue Engineering Applications / Concepts in Material Development / Collagen and Gelatin / Fibrin / Elastin / Hyaluronic Acid / Silk / Alginate / Chitosan / Review of Previous Work / Engineered Polypeptides for Tissue Engineering / Collagen-Inspired Polypeptide Materials / Elastin-Inspired Polypeptide Materials 25I / Silk-Inspired Polypeptide Materials / Polypeptide Materials Self-Assembled Through & alpha;-Helical Domains / Bioactive and Dynamic Materials / Biosynthetic Incorporation of Non-natural Amino Acid Analogs for Engineering Polypeptide Materials / Cartilage Engineering: Current Status and Future Trends / Cartilage Tissue: Structure, Function, and Disease / Cellular and Extracellular Matrix Components / Proper Tissue Function and Response to Stress / Aged and Damaged Tissue / Need for Repair and Regeneration Strategies / Current Standards of Care and Limitations / Current Treatments in Cartilage Repair / Limitations of Current Standard Practices and Need for Engineering Approaches / Cartilage Engineering / Requirements of an Engineered Construct / Biomaterials and Cells for Cartilage Engineering / Engineered Constructs in Clinical Trials and Early Applications / Current Research Efforts / Zonal Cartilage Engineering / Stem Cells / Dynamic Culture Systems / Biomaterials for Regeneration of Tendons and Ligaments / Tissue Overview and Requirements / Physiology and Mechanical Properties / Structure 31I / Interfaces with Other Orthopaedic Tissues / Injury and Repair / Current Techniques for Reconstruction and Tissue Engineering / Current Surgical Management and Reconstruction of Tendons and Ligaments / Biomaterials for Tissue Engineering of Tendons and Ligaments / Conclusions and Future Work / Materials for Bone Graft Substitutes and Osseous Tissue Regeneration / Current Bone Grafting Materials / Demineralized Bone Matrix / Calcium Phosphate Ceramics and Bioactive Glasses / Natural and Synthetic Polymers / New Developments in Bone Grafting Materials / Self-Assembled Biomimetic Materials / Nanocomposite Scaffolds (Collagen) / Nanocomposite Scaffolds (Synthetics) / Nanocomposite Scaffolds (Natural Materials) / Microsphere-Based Scaffolds / Nanophase Ceramics and Material Properties/Processing / Fibrocartilage Tissue Engineering / Tissue Overview/Requirements / Architecture / Biocompatibility / Bioactive Cues / Mechanical Function / Deliverability / Aligned/Microengineered Anisotropic Materials / Cell Adhesion and Targeted Signalling / Delivery Systems / Ultimate Engineered Fibrocartilage: One Author's Guess / Liver Tissue Engineering / Concepts in Liver Tissue Engineering / Liver Anatomy, Physiology and Diseases / Cell Source for Liver Tissue Engineering / Methods and Biomaterials for Ex Vivo Primary Hepatocyte Culture / Review of Previous Work of Liver Support Systems / Artificial/Bioartificial Liver / Hepatocyte Transplantation and Transplantable Liver Constructs / Cardiac Tissue Engineering / Cardiac Tissue Overview and Requirements for Successful Tissue Engineering / Healthy Myocardium / Myocardial Infarction and Heart Failure / Current Clinical Treatment Methods / Emerging Treatment Options / Requirements for Successful Myocardial Regeneration / Cell Injection / In Vitro Cardiac Tissue Engineering / Summary / Biomaterials Approaches in Vascular Engineering: a Review of Past and Future Trends / Importance of Vascularization / Cell Sources / Angiogenic Growth Factors / Scaffold Design / Concepts in Material Development and Tissue Requirements / Biomimetic Materials: A Lesson from Postnatal Angiogenesis / Natural and Synthetic Biomaterials / Cell Adhesion Regulates Vacuole Formation / Cell-Mediated Degradation Allows Lumen Formation / GFs and Oxygen Tension / Tube Stabilization by Prevascular Cells / Biomechanical Control Over Vascular Morphogenesis / Hydrogels to Control Vascular Differentiation / Biomaterials for GFs and Gene Delivery / Biomaterials for Inducing Prevascularization / Microfabrication of Vascular Networks / Neural Tissue Engineering / Tissues in Question and How They are Damaged / Technologies in Clinical Use and in Clinical Trials / Nerve Grafts: Autografts and Allografts / Decellularized Nerve grafts / Tubes and Conduits / Cellular Therapies / Pharmacological Therapies / Early Approaches: Leveraging the Regeneration Seen in the PNS / Leveraging the Regeneration Seen in the Neonate to Promote Repair in the Adult / Polymers for SCI More Broadly / Role of Collaborations in Achieving These Goals / What We Have Not Covered / Controlling Stem Cells with Biomaterials / Biochemical Cues / ECM-Derived Biomaterials / Natural Polymers / Hybrid Materials / Functionalization with Biochemical Cues / Synthetic Biomaterials / Biomaterials as a Reservoir of Growth Factors / Biomaterials for Immunomodulation / Biophysical Cues / Mechanical Properties of Biomaterials / Biomaterials for Micro- and Nano-Scale Cues / Two-Dimensional Cultures Versus Three-Dimensional Cultures / Conclusion and Future Directions / Translation of New Tissue Engineering Materials to Clinical Application / Conceptualization and Preclinical Activities / Development and Design Control: Engineering Rigor and Quality Systems Implementation / Applying Design Controls / Design and Development Planning / Design Inputs / Design Outputs / Design Review / Design Verification / Design Validation / Design Transfer / Design Changes / Design History File / Regulatory Strategy and Evidence Generation / Marketing, Commercialization and Post-market Surveillance / |