Screen LibraryDrug transporters molecular characterization and role in drug disposition /
A comprehensive guide to drug transporters that influence the absorption, distribution, and elimination of drugs in the body. The development of powerful expression cloning and genome analysis techniques has facilitated the molecular identification and characterization of numerous transporters that...
Saved in:
| Corporate Authors: | |
|---|---|
| Group Author: | ; |
| Published: |
|
| Literature type: | Electronic eBook |
| Language: | English |
| Series: |
Wiley series in drug discovery and development
|
| Subjects: | |
| Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9780470140505 |
| Summary: |
A comprehensive guide to drug transporters that influence the absorption, distribution, and elimination of drugs in the body. The development of powerful expression cloning and genome analysis techniques has facilitated the molecular identification and characterization of numerous transporters that play a crucial role in drug disposition. Explaining the principles of drug transport and the associated techniques, Drug Transporters: Molecular Characterization and Role in Drug Disposition:.:. ;. Provides a comprehensive overview of drug transporters. ;. Includes specific descriptions of transpo |
| Carrier Form: | xvi, 889 pages : illustrations (some color) ; 25 cm. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780470140505 047014050X 9780470140499 0470140496 1280956968 9781280956966 |
| Index Number: | QP552 |
| CLC: | Q51 |
| Contents: |
Overview of drug transporter families / Guofeng You and Marilyn E. Morris -- Organic cation transporters / Thomas J. Urban and Kathleen M. Giacomini -- Organic cation/carnitine transporters / Ijaz A. Qureshi [and others] -- Organic anion transporters / Megha Nagle [and others] -- Organic anion-transporting polypeptides / Rommel G. Tirona and Richard B. Kim -- Mammalian oligopeptide transporters / Stephen M. Carl [and others] -- Monocarboxylate transporters / Justin A. Spanier and Lester R. Drewes -- Nucleoside transporters : CNTs and ENTs / Li Xia, Mingyan Zhou, and Joanne Wang -- Bile acid Drug transport in the kidney / Naohiko Anzai and Hitoshi Endou -- Drug transporters in the intestine / Yaming Su and Patrick J. Sinko -- Regulation of drug transporter activity / Mei Hong and Guofeng You -- Experimental approaches to the study of drug transporters / Yoshiyuki Kubo, Yukio Kato, and Akira Tsuji -- In vitro-in vivo scale-up of drug transport activities / Kazuya Maeda and Yuichi Sugiyama -- Age- and gender-related differences in xenobiotic transporter expression / Curtis D. Klaassen and Xingguo Cheng -- Polymorphisms of drug transporters and clinical relevance / Leslie W. Chinn, |