Multivariate analyses of codon usage biases /
A complete case study with all coding sequences from the bacteria Borrellia burgdorferi illustrates how multivariate analyses reveals evolutionary mechanisms acting at the molecular level. They are either mutationnal (symmetric and asymmetric directionnal mutation pressure) or selective (selection a...
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Main Authors: | |
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Corporate Authors: | |
Published: |
ISTE Press Ltd ; Elsevier Ltd,
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Publisher Address: | London, UK : Kidlington, Oxford, UK : |
Publication Dates: |
2018. ©2018 |
Literature type: | eBook |
Language: | English |
Series: |
Statistics for bioinformatics set
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Subjects: | |
Online Access: |
https://www.sciencedirect.com/science/book/9781785482960 |
Summary: |
A complete case study with all coding sequences from the bacteria Borrellia burgdorferi illustrates how multivariate analyses reveals evolutionary mechanisms acting at the molecular level. They are either mutationnal (symmetric and asymmetric directionnal mutation pressure) or selective (selection against head-on collisions or linked to gene expressivity or subcellular location). |
Carrier Form: | 1 online resource. |
Bibliography: | Includes bibliographical references and index. |
ISBN: |
9780128172513 0128172517 |
Index Number: | QH390 |
CLC: | Q349 |
Contents: |
Front Cover; Multivariate Analyses of Codon Usage Biases; Copyright; Contents; Acknowledgments; Introduction; Chapter 1. Introduction to Correspondence Analysis; 1.1. Chapter objectives; 1.2. Metric choice; 1.3. Properties; Chapter 2. Global Correspondence Analysis; 2.1. Data set; 2.2. Running global correspondence analysis; 2.3. The missing factor F0; 2.4. First factor; 2.5. Second and third factors; 2.6. Fourth and fifth factors; Chapter 3. Within and Between Correspondence Analysis; 3.1. Running the analyses; 3.2. Synonymous codon usage (WCA); 3.3. Amino acid usage (BCA) Chapter 4. Internal Correspondence Analysis4.1. Running the analyses; 4.2. Synonymous codon usage; 4.3. Non-synonymous codon usage; Conclusion; Appendices; Appendix 1; A1.1. Introduction; A1.2. Chapter 1; A1.3. Chapter 2; A1.4. Chapter 3; A1.5. Chapter 4; Appendix 2; A2.1. Session information; References; Index; Back Cover |