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Multivariate analyses of codon usage biases /

A complete case study with all coding sequences from the bacteria Borrellia burgdorferi illustrates how multivariate analyses reveals evolutionary mechanisms acting at the molecular level. They are either mutationnal (symmetric and asymmetric directionnal mutation pressure) or selective (selection a...

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Bibliographic Details
Main Authors: Lobry, Jean R.
Corporate Authors: Elsevier Science & Technology.
Published: ISTE Press Ltd ; Elsevier Ltd,
Publisher Address: London, UK : Kidlington, Oxford, UK :
Publication Dates: 2018.
©2018
Literature type: eBook
Language: English
Series: Statistics for bioinformatics set
Subjects:
Molecular evolution.
Gene expression.
Genomics.
SCIENCE > Biochemistry. > Biochemistry.
Electronic books.
Online Access: https://www.sciencedirect.com/science/book/9781785482960
Summary: A complete case study with all coding sequences from the bacteria Borrellia burgdorferi illustrates how multivariate analyses reveals evolutionary mechanisms acting at the molecular level. They are either mutationnal (symmetric and asymmetric directionnal mutation pressure) or selective (selection against head-on collisions or linked to gene expressivity or subcellular location).
Carrier Form: 1 online resource.
Bibliography: Includes bibliographical references and index.
ISBN: 9780128172513
0128172517
Index Number: QH390
CLC: Q349
Contents: Front Cover; Multivariate Analyses of Codon Usage Biases; Copyright; Contents; Acknowledgments; Introduction; Chapter 1. Introduction to Correspondence Analysis; 1.1. Chapter objectives; 1.2. Metric choice; 1.3. Properties; Chapter 2. Global Correspondence Analysis; 2.1. Data set; 2.2. Running global correspondence analysis; 2.3. The missing factor F0; 2.4. First factor; 2.5. Second and third factors; 2.6. Fourth and fifth factors; Chapter 3. Within and Between Correspondence Analysis; 3.1. Running the analyses; 3.2. Synonymous codon usage (WCA); 3.3. Amino acid usage (BCA)
Chapter 4. Internal Correspondence Analysis4.1. Running the analyses; 4.2. Synonymous codon usage; 4.3. Non-synonymous codon usage; Conclusion; Appendices; Appendix 1; A1.1. Introduction; A1.2. Chapter 1; A1.3. Chapter 2; A1.4. Chapter 3; A1.5. Chapter 4; Appendix 2; A2.1. Session information; References; Index; Back Cover

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