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Chemistry and biochemistry of oxygen therapeutics from transfusion to artificial blood /

Scientists are developing oxygen therapeutics, or "blood substitutes," with the same oxygen-carrying capability as blood, that can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. This book links the underlying biochemical principles of...

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Bibliographic Details
Group Author: Mozzarelli, Andrea; Bettati, Stefano
Published:
Literature type: Electronic eBook
Language: English
Subjects:
Oxygen therapy
Blood Substitutes
Oxygen > Physiological effect
Oxygen > Physiological transport
MEDICAL > Pharmacology
Electronic books
Online Access: http://onlinelibrary.wiley.com/book/10.1002/9781119975427
Summary: Scientists are developing oxygen therapeutics, or "blood substitutes," with the same oxygen-carrying capability as blood, that can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. This book links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development, starting with the observation that an oxygen therapeutic agent can be developed only upon a deep understanding of oxygen and nitric oxide, homeostasis and regulation, and the well-documented correlations between adverse
Carrier Form: 1 online resource (xxiv, 442 pages, [8] pages of color plates)
Bibliography: Includes bibliographical references and index.
ISBN: 9781119975427 (electronic bk.)
1119975425 (electronic bk.)
9781119975434 (electronic bk.)
1119975433 (electronic bk.)
Index Number: RM666
CLC: R459.6
Contents: Introduction / Richard B Weiskopf -- Oxygen: Chemistry, Biochemistry, Physiology and Toxicity. Hemoglobin Reactivity and Regulation / Stefano Bettati, Andrea Mozzarelli -- The Major Physiological Control Mechanisms of Blood Flow and Oxygen Delivery / Raymond C Koehler -- The Main Players: Hemoglobin and Myoglobin; Nitric Oxide and Oxygen / Tim J McMahon, Joseph Bonaventura -- The Role of Reactive Oxygen and Nitrogen Species in Ischemia/Reperfusion Injury / Ester Spagnolli, Warren M Zapol -- Medical Needs for Oxygen Supply. Acute Traumatic Hemorrhage and Anemia / Lena M Napolitano -- Diagnosi

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