Screen LibraryIron-sulfur clusters in chemistry and biology /
This volume on iron-sulfur clusters includes chapters that cover the history of the discovery of iron-sulfur clusters in the 1960s to discoveries of their role in the enzyme, aconitase (1980s), and numerous other proteins. It explains basic chemistry principles, how microbes, plants, and animals syn...
Saved in:
| Corporate Authors: | |
|---|---|
| Group Author: | |
| Published: |
De Gruyter,
|
| Publisher Address: | Berlin/Boston : |
| Publication Dates: | [2014] |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1515/9783110308426 http://www.degruyter.com/doc/cover/9783110308426.jpg |
| Summary: |
This volume on iron-sulfur clusters includes chapters that cover the history of the discovery of iron-sulfur clusters in the 1960s to discoveries of their role in the enzyme, aconitase (1980s), and numerous other proteins. It explains basic chemistry principles, how microbes, plants, and animals synthesize these complex prosthetic groups, and why it is important to understand the chemistry and biogenesis of FeS proteins. |
| Carrier Form: |
1 online resource(xxiv,648pages) : illustrations Also available in print edition. |
| ISBN: | 9783110308426 |
| Index Number: | QP535 |
| CLC: | Q591.2 |
| Contents: |
Frontmatter -- Preface -- Tracey A. Rouault biography -- Contents -- Contributing authors -- 1. Iron-sulfur proteins: a historical perspective / 2. Chemistry of iron-sulfur clusters / 3. Quantitative interpretation of EPR spectroscopy with applications for iron-sulfur proteins / 4. The utility of M ssbauer spectroscopy in eukaryotic cell biology and animal physiology / 5. The interstitial carbide of the nitrogenase M-cluster: insertion pathway and possible function / 6. The iron-molybdenum cofactor of nitrogenase / 7. Biotin synthase: a role for iron-sulfur clusters in the radical-mediated generation of carbon-sulfur bonds / 8. Molybdenum-containing iron-sulfur enzymes / 9. The role of iron-sulfur clusters in the biosynthesis of the lipoyl cofactor / 10. Iron-sulfur clusters and molecular oxygen: function, adaptation, degradation, and repair / 11. A retrospective on the discovery of [Fe-S] cluster biosynthetic machineries in Azotobacter vinelandii / 12. A stress-responsive Fe-S cluster biogenesis system in bacteria the suf operon of Gammaproteobacteria / 13. Sensing the cellular Fe-S cluster demand: a structural, functional, and phylogenetic overview of Escherichia coli IscR / 14. Fe-S assembly in Gram-positive bacteria / 15. Fe-S cluster assembly and regulation in yeast / 16. The role of Fe-S clusters in regulation of yeast iron homeostasis / 17. Biogenesis of Fe-S proteins in mammals / 18. Iron-sulfur proteins and human diseases / 19. Connecting the biosynthesis of the molybdenum cofactor, Fe-S clusters, and tRNA thiolation in humans / 20. Iron-sulfur proteins and genome stability / 21. Eukaryotic iron-sulfur protein biogenesis and its role in maintaining genomic integrity / 22. Iron-sulfur cluster assembly in plants / 23. Origin and evolution of Fe-S proteins and enzymes / Index. |