Screen LibraryResearch on new generation tumor markers /
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| Group Author: | |
|---|---|
| Published: |
Nova Medicine and Health,
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| Publisher Address: | New York, NY : |
| Publication Dates: | [2018] |
| Literature type: | Book |
| Language: | English |
| Series: |
Cancer etiology, diagnosis and treatments
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| Subjects: | |
| Carrier Form: | viii, 282 pages : illustrations (some color) ; 26 cm. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9781536143676 1536143677 |
| Index Number: | RC270 |
| CLC: | R730.4 |
| Call Number: | R730.4/R432-1 |
| Contents: |
Intro; Contents; Preface; Chapter 1; Commonly Used Tumor Markers and Their Limitations; Abstract; Introduction; Testing for Tumor Markers; Accuracy; Sensitivity; Specificity; Anaplastic Lymphoma Kinase Gene (ALK) Fusions; Alpha-Fetoprotein (AFP); Beta-2 Microglobulin; Beta-Human Chorionic Gonadotropin (β-hCG); BRCA1 and BRCA2 Gene Mutations; BCR-ABL Fusion Gene; BRAF V600 Mutation; C-Kit/CD117; CA 15-3 and CA 27.29; CA19-9; CA-125; Calcitonin; Carcinoembryonic Antigen (CEA); B-Lymphocyte Antigen CD20; Chromogranin A (CgA); Chromosomes 3, 7, 17, 9p21 IntroductionNa+-K+ Pump; Structure of the Na+-K+ Pump and FXYD Protein; Paradigms for Regulation of the Na+-K+ Pump; Protein Phosphorylation Signalling Pathways; Protein Kinase-Dependent Redox Regulation of the Na+-K+ Pump; Na+-K+ Pump as a Target for Cancer; FXYD3 Proteins and Reversal of B1 Pump Subunit Glutathionylation and Pump Inhibition; Role of FXYD Proteins Involved in the Direction of Na+/K+ Pump in Cancer; Observational Studies on FXYD3 Protein and Cancer Treatment Response; FXYD3 as A Promising Biomarker in Cancer; FXYD3 as a Therapeutic Target in Cancer FXYD3 as Personalized Drug for Cancer TreatmentsLast Word; Références; Chapter 3; Circulating Cell-Free DNA; Abstract; Introduction; History; Biology of Cell-Free DNA; Origins of Cell-Free DNA; Mechanisms of Release and Clearance of Cell-Free DNA in the Blood; Clinical Application of cfDNA/ctDNA; In Autoimmune Diseases; In Transplantation; In Trauma and Sepsis; In Non-Invasive Prenatal Diagnosis; In Cancer; Methods for Detecting ctDNA; Conclusion; References; Chapter 4; Circulating Free DNA in Hepatobiliary and Gastrointestinal Malignancies; Abstract; Introduction Circulating Markers in Gastrointestinal MalignanciesColorectal Cancer; Esophageal Cancer; Gastric Cancer; Gastrointestinal Stromal Tumors (GIST); Pancreatic Cancer; Hepatocellular Carcinoma; Gallbladder Carcinoma; Methods for Quantification of cfDNA; References; Chapter 5; microRNAs in Cancer Management; Abstract; 1. MicroRNA Biogenesis and Function; 2. MicroRNAs in Cancer; 2.1. Lung Cancer; 2.2. Breast Cancer; 2.3. Prostate Cancer; 2.4. Colorectal Cancer; 3. MicroRNAs as Biomarkers of Diagnosis and Prognosis; 3.1. let-7 Family; 3.2. miR-10b; 3.3. miR-16; 3.4. miR-17-92 Cluster |