Screen LibraryTheranostics, Gallium-68, and other radionuclides : a pathway to personalized diagnosis and treatment /
This book is based on contributions presented at the 1st World Congress on Gallium-68 and Peptide Receptor Radionuclide Therapy, which examined recent developments in theranostics - the emerging field of molecular targeting of vectors that can be used for both diagnosis and therapy, when modified ac...
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| Corporate Authors: | |
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| Group Author: | ; |
| Published: |
Springer,
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| Publisher Address: | Berlin ; New York : |
| Publication Dates: | 2013. |
| Literature type: | eBook |
| Language: | English |
| Series: |
Recent results in cancer research,
v.194 |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1007/978-3-642-27994-2 |
| Summary: |
This book is based on contributions presented at the 1st World Congress on Gallium-68 and Peptide Receptor Radionuclide Therapy, which examined recent developments in theranostics - the emerging field of molecular targeting of vectors that can be used for both diagnosis and therapy, when modified accordingly. The focus of this book is on the rapidly developing research into and clinical applications of gallium-68 and other generator-produced PET radionuclides in the personalized diagnosis and treatment of neuroendocrine tumors and other diseases. In addition, new PET radiopharmaceuticals are considered, and the latest ideas and concepts, presented. Theranostics embodies both molecular and personalized medicine. It is at the cutting edge of medicine, and the contents of this volume will be of interest to chemists, physicians, and investigators dealing with generators, PET radiochemistry, molecular imaging, and radionuclide therapy. |
| Carrier Form: | 1 online resource. |
| Bibliography: | Includes bibliographical references. |
| ISBN: |
9783642279942 (electronic bk.) 3642279945 (electronic bk.) |
| Index Number: | RM858 |
| CLC: | R817 |
| Contents: |
Generators -- sGe/ sGa Generators: Past, Present, and Future / Overview and Perspectives on Automation Strategies in sGa Radiopharmaceutical Preparations / Post-Processing via Cation Exchange Cartridges: Versatile Options / sGa Generator Integrated System: Elution-Purification-Concentration Integration / Purification and Labeling Strategies for sGa from sGe/ sGa Generator Eluate / 67Ga and sGa Purification Studies: Preliminary Results / Radiochemistry and Radiopharmacy -- The Diversity of sGa-Based Imaging Agents / Nanoparticles and Phage Display Selected Peptides for Imaging and Therapy of Cancer / Click-Cyclized sGa-Labeled Peptides for Molecular Imaging and Therapy: Synthesis and Preliminary In Vitro and In Vivo Evaluation in a Melanoma Model System / Early Experience with sGa-DOTATATE Preparation / sGa-Radiopharmaceuticals for PET Imaging of Infection and Inflammation / sGa-Labeled Bombesin Analogs for Receptor-Mediated Imaging / A Novel sGa-Labeled Pteroic Acid-Based PET Tracer for Tumor Imaging via the Folate Receptor / Measurement of Protein Synthesis: In Vitro Comparison of sGa-DOTA-Puromycin, [ sH]Tyrosine, and 2-Fluoro-[ sH]tyrosine / Hypoxia Imaging Agents Labeled with Positron Emitters / sLu/ sYIntermediate-Affinity Monoclonal Antibodies Targeting EGFR and HER2/c-neu: Preparation and Preclinical Evaluation / Molecular Imaging Using Ga-68 labeled Tracers -- Divergent Role of sGa-Labeled Somatostatin Analogs in the Workup of Patients with NETs: AIIMS Experience / Differential Uptake of sGa-DOTATOC and sGa-DOTATATE in PET/CT of Gastroenteropancreatic Neuroendocrine Tumors / High Uptake of sGa-DOTATOC in Spleen as Compared to Splenosis: Measurement by PET/CT / Rare Metastases Detected by sGa-Somatostatin Receptor PET/CT in Patients with Neuroendocrine Tumors / Comparison of Different Positron Emission Tomography Tracers in Patients with Recurrent Medullary Thyroid Carcinoma: Our Experience and a Review of the Literature / PET Lung Ventilation/Perfusion Imaging Using sGa Aerosol (Galligas) and sGa-Labeled Macroaggregated Albumin / Combined PET/MR Imaging Using sGa-DOTATOC for Radiotherapy Treatment Planning in Meningioma Patients / Targeted Radiotherapy (Peptide Receptor Radionuclide Therapy) and Dosimetry -- A Rare Case of a Large Spinal Meningioma with Mediastinal Extension and Malignant Behavior Classified Histologically as Benign / Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors in Germany: First Results of a Multi-institutional Cancer Registry / Polish Experience in Peptide Receptor Radionuclide Therapy / PRRT as Neoadjuvant Treatment in NET / Intraoperative Somatostatin Receptor Detection After Peptide Receptor Radionuclide Therapy with sLu- and sY-DOTATOC (Tandem PRRNT) in a Patient with a Metastatic Neuroendocrine Tumor / Personalized Image-Based Radiation Dosimetry for Routine Clinical Use in Peptide Receptor Radionuclide Therapy: Pretherapy Experience / The Bad Berka Dose Protocol: Comparative Results of Dosimetry in Peptide Receptor Radionuclide Therapy Using sLu-DOTATATE, sLu-DOTANOC, and sLu-DOTATOC / 4D SPECT/CT Acquisition for 3D Dose Calculation and Dose Planning in sLu-Peptide Receptor Radionuclide Therapy: Applications for Clinical Routine / Peptide Receptor Radionuclide Therapy with sLu Labeled Somatostatin Analogs DOTATATE and DOTATOC: Contrasting Renal Dosimetry in the Same Patient / Ge/ Ga Generators: Past, Present, and Future / Overview and Perspectives on Automation Strategies in Ga Radiopharmaceutical Preparations / Ga Generator Integrated System: Elution-Purification-Concentration Integration / Purification and Labeling Strategies for Ga from Ge/ Ga Generator Eluate / 67Ga and Ga Purification Studies: Preliminary Results / The Diversity of Ga-Based Imaging Agents / Click-Cyclized Ga-Labeled Peptides for Molecular Imaging and Therapy: Synthesis and Preliminary In Vitro and In Vivo Evaluation in a Melanoma Model System / Early Experience with Ga-DOTATATE Preparation / Ga-Radiopharmaceuticals for PET Imaging of Infection and Inflammation / Ga-Labeled Bombesin Analogs for Receptor-Mediated Imaging / A Novel Ga-Labeled Pteroic Acid-Based PET Tracer for Tumor Imaging via the Folate Receptor / Measurement of Protein Synthesis: In Vitro Comparison of Ga-DOTA-Puromycin, [ H]Tyrosine, and 2-Fluoro-[ H]tyrosine / Lu/ YIntermediate-Affinity Monoclonal Antibodies Targeting EGFR and HER2/c-neu: Preparation and Preclinical Evaluation / Divergent Role of Ga-Labeled Somatostatin Analogs in the Workup of Patients with NETs: AIIMS Experience / Differential Uptake of Ga-DOTATOC and Ga-DOTATATE in PET/CT of Gastroenteropancreatic Neuroendocrine Tumors / High Uptake of Ga-DOTATOC in Spleen as Compared to Splenosis: Measurement by PET/CT / Rare Metastases Detected by Ga-Somatostatin Receptor PET/CT in Patients with Neuroendocrine Tumors / PET Lung Ventilation/Perfusion Imaging Using Ga Aerosol (Galligas) and Ga-Labeled Macroaggregated Albumin / Combined PET/MR Imaging Using Ga-DOTATOC for Radiotherapy Treatment Planning in Meningioma Patients / Intraoperative Somatostatin Receptor Detection After Peptide Receptor Radionuclide Therapy with Lu- and Y-DOTATOC (Tandem PRRNT) in a Patient with a Metastatic Neuroendocrine Tumor / The Bad Berka Dose Protocol: Comparative Results of Dosimetry in Peptide Receptor Radionuclide Therapy Using Lu-DOTATATE, Lu-DOTANOC, and Lu-DOTATOC / 4D SPECT/CT Acquisition for 3D Dose Calculation and Dose Planning in Lu-Peptide Receptor Radionuclide Therapy: Applications for Clinical Routine / Peptide Receptor Radionuclide Therapy with Lu Labeled Somatostatin Analogs DOTATATE and DOTATOC: Contrasting Renal Dosimetry in the Same Patient / |