Screen LibraryApoptosis, genomic integrity, and cancer
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| Main Authors: | |
|---|---|
| Published: |
Jones and Bartlett Publishers,
|
| Publisher Address: | Sudbury, Mass. |
| Publication Dates: | c2006. |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Carrier Form: | xviii, 422 p.: ill. ; 26 cm. |
| ISBN: |
0763745413 (alk. paper) 9780763745417 (alk. paper) |
| Index Number: | Q25 |
| CLC: |
Q25-05 R730.23 R353 |
| Call Number: | R363/V259 |
| Contents: |
Includes bibliographical references and index. Morphology and occurrence of apoptosis -- Recognition and disposal of the apoptotic bodies -- Agents that trigger apoptosis -- Genes and gene products in apoptosis of C. elegans -- The Bc1-2 family -- Interleukin 1-B [beta] Converting enzyme (ICE) and caspases -- The cytochrome c-Dependent pathway to apoptosis -- Inhibitor of apoptosis proteins (IAPs) -- The p53 Gene -- Integrity of the genome and programmed cell death -- Enzymes potentially involved in P53 activation -- P53 and the cell cycle -- Cell cycle checkpoints -- Cell cycle arrest -- P53 transactivation of GADD45 and MDM2 -- The P53 family and apoptosis -- Tumor transorming growth factors and cancer -- Protein tyrosine kinase receptors and cancer -- The oncogenic GTPases -- Non-receptor protein kinases and cancer -- The PiK3/AKT pathway cancer and apoptosis -- Transcription factors and cancer -- Cancer and genomic instability -- Cancer and genomic instability: mismatch repair and cancer -- Role of Fanconi anemia, breast cancer, and bloom syndrome genes in oncogenesis -- Cancer and apoptosis. |