Role of nutraceuticals in cancer chemosensitization /

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Bibliographic Details
Group Author: Bharti, Alok Chandra (Editor); Aggarwal, Bharat B., 1950- (Editor)
Published: Elsevier/Academic Press,
Publisher Address: London, United Kingdom :
Publication Dates: [2018]
Literature type: Book
Language: English
Series: Cancer sensitizing agents for chemotherapy, volume 2
Subjects:
Carrier Form: xvii, 379 pages : color illustrations, color portraits ; 24 cm.
Bibliography: Includes bibliographical references and index.
ISBN: 9780128164723
0128164727
9780128123737
0128123737
Index Number: RC271
CLC: R730.5
Call Number: R730.5/R745-3
Contents: Machine generated contents note: 1.Pathways Linked to Cancer Chemoresistance and Their Targeting by Nutraceuticals / Bharat Bhushan Aggarwal -- Abstract -- Introduction -- Chemotherapy -- Chemoresistance: Problem in Curing Cancer -- Mechanism of Chemoresistance -- Chemosensitization: An Approach to Target Cancer -- Nutraceuticals as Chemosensitizers: Opportunities and Challenges -- Conclusion -- Conflict of Interest -- Acknowledgments -- References -- 2.The Potential of Curcumin: A Multitargeting Agent in Cancer Cell Chemosensitization / Ajaikumar B. Kunnumakkara -- Abstract -- Introduction -- Chemosensitization Studies of Curcumin in Different Cancers -- Conclusion -- Conflict of Interest -- Acknowledgment -- References -- Further Reading -- 3.Role of Resveratrol in Chemosensitization of Cancer / Kuzhuvelil B. Harikumar -- Abstract -- Introduction -- Source and Chemistry of Resveratrol -- Possible Molecular Mechanisms of Chemoresistance in Cancer
Note continued: Chemosensitization Studies Using Resveratrol in Vitro -- Chemosensitization Studies Using Resveratrol in Vivo -- Human Clinical Trials Involving Resveratrol in Cancer -- Conclusion and Future Perspective -- References -- Further Reading -- 4.Role of Tocotrienols in Chemosensitization of Cancer / Mokenge P. Malafa -- Abstract -- Introduction -- Source and Chemistry of Tocotrienols -- Molecular Targets of Tocotrienols in Cancer -- Mechanisms of Anticancer Action of Tocotrienols -- Chemosensitization by Tocotrienols -- Chemosensitization In Vitro -- Chemosensitization In Vivo -- Chemosensitization in Human -- Conclusion -- References -- 5.Chemosensitization by Ursolic Acid: A New Avenue for Cancer Therapy / Bharat Bhushan Aggarwal -- Abstract -- Introduction -- Chemosensitization of Cancer Cells -- Safety and Efficacy -- Conclusion and Future Direction -- Acknowledgment -- References -- 6.Role of Fisetin in Chemosensitization / Bokyung Sung -- Abstract
Note continued: Introduction -- Chemistry and Sources of Fisetin -- Molecular Targets of Fisetin -- Chemosensitization by Fisetin -- Conclusion -- Conflict of Interest -- References -- 7.Role of Celastrol in Chemosensitization of Cancer / Gautam Sethi -- Abstract -- Introduction -- Biological Source of Celastrol and Its Chemistry -- Molecular Targets of Celastrol and Its Potential Mechanism(s) of Action -- Anticancer and Chemosensitizing Effects of Celastrol -- Conclusions -- Conflict of Interest -- Acknowledgments -- References -- 8.Role of Gambogic Acid in Chemosensitization of Cancer / Manoj K. Pandey -- Abstract -- Introduction -- Source and Chemistry of GA -- Molecular Targets of GA -- Chemo-Sensitization by GA -- Conclusion -- References -- 9.Role of Catechins in Chemosensitization / Anju Shrivastava -- Abstract -- Introduction -- Sources of Catechins -- Structure and Chemistry of Catechins -- Molecular Targets of the Catechin -- Chemosensitization in Vitro
Note continued: Chemosensitization in Vivo -- Human Trials -- Implication of Catechins in Other Diseases -- Conclusion -- Conflict of Interest -- Acknowledgment -- References -- Further Reading -- 10.Anticancer Attributes of Silibinin: Chemo- and Radiosensitization of Cancer / Rana P. Singh -- Abstract -- Introduction -- Structural Composition and Bioavailability of Silymarin/Silibinin -- Targeting of Various Attributes of Cancer Growth and Progression -- Silibinin as Chemosensitizer for Cancer Cells -- Silibinin as Radiosensitizer for Cancer Cells -- Conclusions -- References -- 11.Berberine as an Adjuvant and Sensitizer to Current Chemotherapy / Anjali Bhat -- Abstract -- Introduction -- Source and Chemistry -- Evidence Showing the Potential of Berberine as a Chemosensitizer -- Hormetic Effects of Berberine in In Vitro Studies -- Chemosensitization In Vivo and Other Beneficial Properties -- Berberine in Human Trials -- Conclusion -- Conflict of Interest
Note continued: Acknowledgments -- References -- 12.Role of Emodin in Chemosensitization of Cancer / Vipin Rai -- Abstract -- Introduction -- Anti-cancer Activities of Emodin -- Anti-cancer Activities of Emodin Analogues -- Chemosensitization of Tumors by Emodin -- Conclusions -- Acknowledgments -- References -- 13.Role of Piperine in Chemoresistance / Navneet Agnihotri -- Abstract -- Introduction -- Sources and Chemistry of Piperine -- Piperine Extraction and Quantification -- Medicinal & Pharmacological Activities of Piperine -- Mechanism of Action of Piperine -- Chemoresistance and Chemosensitisation -- Interactions of Piperine With Chemotherapeutic Drugs -- Conclusion -- References -- Further Reading -- 14.Role of Deguelin in Chemoresistance / Shivakumari Asha Nair -- Abstract -- Introduction -- Source and Chemistry of Deguelin -- Molecular Targets of Deguelin -- Chemosensitization by Deguelin -- Conclusion -- Acknowledgements -- References
Note continued: 15.Garcinol: Preclinical Perspective Underpinning Chemo- and Radiosensitization of Cancer / Shivani B. Paruthy -- Abstract -- Introduction -- Garcinol Bioavailability -- Garcinol: Therapeutic Targets -- Systemic Anticancer and Chemo-Sensitizing Effects of Garcinol -- Garcinol and TRAIL Sensitization -- Garcinol and Radiosensitization -- Garcinol Combination With Other Natural Agents' on Cancer Therapy -- Conclusion -- References -- 16.Chemopreventive and Anticancer Effects of Plumbagin: Novel Mechanism(s) via Modulation of Cellular Redox / Santosh K. Sandur -- Abstract -- Introduction -- Occurrence and Isolation of Plumbagin -- Antioxidant Properties of Plumbagin -- Chemopreventive and Antitumor Properties of Plumbagin -- Antiangiogenic Property of Plumbagin -- Plumbagin Nano-Particle Preparations -- Anti-inflammatory Properties of Plumbagin -- Chemosensitizing Properties of Plumbagin -- Conclusion -- References