Metabolomics by in vivo NMR

This book is unique in linking in vivo 13C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states. Provides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and d...

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Bibliographic Details
Group Author: Shulman, R. G. (Robert Gerson); Rothman, D. L. (Douglas L.)
Published:
Literature type: eBook
Language: English
Subjects:
Online Access: http://onlinelibrary.wiley.com/book/10.1002/0470011505
Summary: This book is unique in linking in vivo 13C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states. Provides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and disease states, e.
Carrier Form: 1 online resource (xiv, 192 pages) : illustrations (some color)
Bibliography: Includes bibliographical references and index.
ISBN: 0470011491 (electronic bk.)
9780470011492 (electronic bk.)
0470011505 (electronic bk.)
9780470011508 (electronic bk.)
Index Number: QP171
CLC: Q493
Contents: In vivo NMR spectroscopy-techniques; direct detection; MRS; kinetics & labels; fluxes; concentrations / R. deGraaf -- MCA for the NMR spectroscopists / D. Fell and D.L. Rothman -- MRS studies of the role of muscle glycogen synthesis pathway in the pathophysiology of type 2 diabetes / D.L. Rothman, J.R.A. Schafer, & R.G. Shulman -- Phosphorylation of allosteric enzymes can serve homeostasis rather than control flux: the example of glycogen synthase / James R.A. Schafer [and others] -- Regulation of glycogen metabolism in muscle during exercise / T. Price, D.L. Rothman and R.G. Shulman -- 13C NMR studies of myocardial glycogen metabolism / M. Laughlin, D.L. Rothman and R.G. Shulman -- Bioenergetics implication of metabolic fluctuation during muscle contraction / Thomas Jue -- Lactate, glycogen and fatigue / R.G. Shulman and D.L. Rothman -- Futile cycling in yeast: how to control gluttony in the midst of plenty / Jan den Hollander and Robert G. Shulman -- Trehalose energetics in yeast spores / Robert G. Shulman and Jan den Hollander -- Metabolic networks in the liver by 2H and 13C NMR / A. Dean Sherry and Craig R. Malloy -- Summarized reflections on metabolism / R.G. Shulman and James R.A. Schafer.