Screen LibraryCancer chemotherapy and biotherapy：principles and practice
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| Group Author: | ; ; |
|---|---|
| Published: |
Wolters Kluwer Health/Lippincott Williams & Wilkins,
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| Publisher Address: | Philadelphia |
| Publication Dates: | c2011. |
| Literature type: | Book |
| Language: | English |
| Edition: | 5th ed. |
| Subjects: | |
| Carrier Form: | xv, 812 p.: ill. (some col.) ; 29 cm. |
| ISBN: |
9781605474311 (hardback : alk. paper) 1605474312 (hardback : alk. paper) |
| Index Number: | R730 |
| CLC: | R730.53 |
| Call Number: | R730.53/C215-1/5th.ed. |
| Contents: |
Includes bibliographical references and index. Clinical strategies for cancer treatment: the role of drugs -- Target identification and drug discovery -- Clinical drug development and marketing approval -- Principles of pharmacokinetics -- Delivering anticancer drugs to brain tumors -- Pharmacogenetics -- Physical barriers to drug delivery -- Antifolates -- 5-fluoropyrimidines -- Cytidine analogues -- Purine antimetabolites -- Hydroxyurea -- Antimitotic drugs -- Alkylating agents -- Platinum analogues -- Bleomycin and other antitumor antibiotics -- Topoisomerase I-targeting drugs -- Topoisomerase II inhibitors: anthracyclines ... "Updated to include the newest drugs and those currently in development, Cancer Chemotherapy and Biotherapy, Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents--their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Chapters emphasize pharmacology and mechanisms of action at the molecular and cellular levels, followed by clinical activity and toxicity, both acute and delayed ... |