Screen LibraryAntiviral drug strategies
By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses. It begins with a general discussion of antiviral strategies, foll...
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| Group Author: | |
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| Published: |
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| Literature type: | Electronic eBook |
| Language: | English |
| Series: |
Methods and principles in medicinal chemistry ;
v. 50 |
| Subjects: | |
| Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9783527635955 |
| Summary: |
By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses. It begins with a general discussion of antiviral strategies, followed by a broad survey of known viral targets, such as reverse transcriptases, proteases, neuraminidases, RNA polymerases, helicases and primases, as well as their known inhibitors. The final section contains several cases studies of recent successful antiviral drug development. Edited by Erik de. |
| Carrier Form: | 1 online resource (xx, 406 pages) : illustrations (some color). |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9783527635955 (electronic bk.) 3527635955 (electronic bk.) 9783527635979 (electronic bk.) 3527635971 (electronic bk.) 1283140918 9781283140911 |
| Index Number: | RS431 |
| CLC: | R978.7 |
| Contents: |
Outlook of the antiviral drug era, now more than 50 years after description of the first antiviral drug / Inhibition of HIV entry / Targeting integration beyond strand transfer: development of second-generation HIV integrase inhibitors / From saquinavir to darunavir: the impact of 10 years of medicinal chemistry on a lethal disease / Acyclic and cyclic nucleoside phosphonates / He |