Screen Libraryp53 : the gene that cracked the cancer code /
All of us have lurking in our DNA a most remarkable gene, which has a crucial job - it protects us from cancer. Known simply as p53, this gene constantly scans our cells to ensure that they grow and divide without mishap, as part of the routine maintenance of our bodies. If a cell makes a mistake in...
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| Main Authors: | |
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| Published: |
Bloomsbury Sigma,
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| Publisher Address: | London : |
| Publication Dates: | 2014. |
| Literature type: | Book |
| Language: | English |
| Series: |
Bloomsbury sigma series ;
book 2 |
| Subjects: | |
| Summary: |
All of us have lurking in our DNA a most remarkable gene, which has a crucial job - it protects us from cancer. Known simply as p53, this gene constantly scans our cells to ensure that they grow and divide without mishap, as part of the routine maintenance of our bodies. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, summoning a repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control, p53 commands the cell to commit suicide. Cancer cannot develop unle |
| Carrier Form: | 287 pages ; 23 cm. |
| Bibliography: | Includes bibliographical references (pages 269-277) and index. |
| ISBN: |
9781472913203 1472913205 |
| Index Number: | RC268 |
| CLC: | R730.5 |
| Call Number: | R730.5/A738 |
| Contents: | Flesh of our own flesh -- The enemy within -- Discovery -- Unseeable biology -- Cloning the gene -- A case of mistaken identity -- A new angle on cancer -- p53 reveals its true colours -- Master switch -- 'Guardian of the genome' -- Of autumn leaves and cell death -- Of mice and men -- The guardian's gatekeeper -- The smoking gun -- Following the fingerprints -- Cancer in the family? -- The Tropeiro connection? -- Jekyll and Hyde -- Cancer and ageing : a balancing act? -- The treatment revolution. |