Prospects for chemoprevention of colorectal neoplasia : emerging role of anti-inflammatory drugs /

The prevention of colorectal cancer is a subject of increasing medical importance, and there have been a number of promising recent developments. This book examines in detail important aspects of the current status and future prospects for chemoprevention of colorectal tumors. Research into the mech...

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Bibliographic Details
Corporate Authors: SpringerLink (Online service)
Group Author: Chan, Andrew T.; Detering, Elmar
Published: Springer,
Publisher Address: Berlin ; New York :
Publication Dates: 2013.
Literature type: eBook
Language: English
Series: Recent results in cancer research, v.191
Subjects:
Online Access: http://dx.doi.org/10.1007/978-3-642-30331-9
Summary: The prevention of colorectal cancer is a subject of increasing medical importance, and there have been a number of promising recent developments. This book examines in detail important aspects of the current status and future prospects for chemoprevention of colorectal tumors. Research into the mechanisms that lead from early colorectal adenoma to colorectal cancer is discussed. The role and modes of action of available drugs such as celecoxib and sulindac are described, and recent data from aspirin trials are analyzed. In addition, the possible impact of nutritional agents with anti-inflammat
Carrier Form: 1 online resource.
Bibliography: Includes bibliographical references.
ISBN: 9783642303319 (electronic bk.)
3642303315 (electronic bk.)
Index Number: RC280
CLC: R735.301
Contents: An Emerging Role for Anti-inflammatory Agents for Chemoprevention /
Mechanistic Aspects of COX-2 Expression in Colorectal Neoplasia /
Mode of Action of Aspirin as a Chemopreventive Agent /
Coxibs: Pharmacology, Toxicity and Efficacy in Cancer Clinical Trials /
COX-2 Active Agents in the Chemoprevention of Colorectal Cancer /
New NSAID Targets and Derivatives for Colorectal Cancer Chemoprevention /
Aspirin in Prevention of Sporadic Colorectal Cancer: Current Clinical Evidence and Overall Balance of Risks and Benefits /
Nutritional Agents with Anti-lnflammatory Properties in Chemoprevention of Colorectal Neoplasia /
Genetics, Inheritance and Strategies for Prevention in Populations at High Risk of Colorectal Cancer (CRC) /