Natural and synthetic biomedical polymers /

"Polymer scientists have made an extensive research for the development of biodegradable polymers which could find enormous applications in the area of medical science. Today, various biopolymers have been prepared and utilized in different biomedical applications. Despite the apparent prolifer...

Full description

Saved in:
Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Kumbar, Sangamesh (Editor); Laurencin, Cato T. (Editor); Deng, Meng (Editor)
Published: Elsevier Science,
Publisher Address: Amsterdam :
Publication Dates: 2014.
Literature type: eBook
Language: English
Edition: First edition.
Subjects:
Online Access: http://www.sciencedirect.com/science/book/9780123969835
Summary: "Polymer scientists have made an extensive research for the development of biodegradable polymers which could find enormous applications in the area of medical science. Today, various biopolymers have been prepared and utilized in different biomedical applications. Despite the apparent proliferation of biopolymers in medical science, the Science and Technology of biopolymers is still in its early stages of development. Tremendous opportunities exist and will continue to exist for the penetration of biopolymers in every facet of medical science through intensive Research and Development. Therefore, this chapter addresses different polymerization methods and techniques employed for the preparation of biopolymers. An emphasis is given to cover the general properties of biopolymers, synthetic protocols and their biomedical applications. In order to make the useful biomedical devices from the polymers to meet the demands of medical science, various processing techniques employed for the development of devices have been discussed. Further, perspectives in this field have been highlighted and at the end arrived at the conclusions. The relevant literature was collected from different sources including Google sites, books and reviews"--
Item Description: Machine generated contents note: Section 1. Synthesis and Characterization 1.1. Polymer Synthesis: the design and synthesis of important classes of polymeric biomaterials involving different monomers will be discussed. 1.2. Characterization of Polymeric Biomaterials: in vitro and in vivo characterization of advanced biomaterials, (cell and tissue interactions with polymeric biomaterials with various physico-chemical, mechanical properties, surface and degradation properties Section 2. Currently Used Materials 2.1. Proteins and poly(amino acids) including collagen, poly(amino acids), elastin and elastin-like polypeptides, albumin, and fibrin 2.2. Polysaccharides including hyaluronic acid, chondroitin sulfate, chitin and chitosan, and alginic acid 2.3. Poly(a-ester)s including polylactides, polyglycolide, poly(lactide-co-glycolide), polycaprolactone, and bacterial polyesters 2.4. Polyurethanes 2.5. Poly(ester amide) 2.6. Poly(ortho esters) 2.7. Polyanhydrides 2.8. Poly(propylene fumarate) 2.9. Polyphosphazenes 2.10. Pseudo poly(amino acid)s 2.11. Polyphosphoester 2.12. Polyacetals 2.13. Poly(ethylene glycol)-based biomaterials 2.14. Dendrimers 2.15. Elastomers Section 3. Biomedical Applications of Polymeric Biomaterials 3.1. Polymeric Biomaterials in Biomedical Implants 3.2. Polymeric Biomaterials in Drug Delivery 3.3. Polymeric Biomaterials in Tissue Engineering 3.4. Polymeric Biomaterials in Medical Diagnostics.
Carrier Form: 1 online resource (402 pages)
Bibliography: Includes bibliographical references and index.
ISBN: 9780123972903
0123972906
Index Number: TP248
CLC: R318.08
Contents: Machine-generated contents note:
Note continued:
Introduction /
Types of Polymerizations /
Addition Polymerization /
Condensation Polymerization /
Metathesis Polymerization /
Techniques of Polymerization /
Solution Polymerization /
Bulk (Mass) Polymerization /
Suspension Polymerization /
Precipitation Polymerization /
Emulsion Polymerization /
Polymers: Properties, Synthesis, and Their Biomedical Applications /
Polycaprolactone /
Polyethylene Glycol /
Polyurethane /
Polydioxanone or Poly-p-Dioxanone /
Poly(Methyl Methacrylate) /
Polyglycolic Acid or Polyglycolide /
Polylactic Acid or Polylactide /
Polylactic-co-Glycolic Acid /
Polyhydroxybutyrate /
Polycyanoacrylates /
Polyvinylpyrrolidone /
Chitosan /
Gelatin /
Carrageenan /
Hyaluronic Acid /
Xanthan Gum /
Acacia Gum /
Alginate /
Processing of Polymers for Biomedical Devices /
Fabrication of Polymer Films /
Spinning Industrial Polymers /
Fabrication of Shaped Polymer Objects /
Calendaring /
Future Perspectives /
Conclusions /
Acknowledgments /
References /
The Hierarchical Characterization Approach /
Bulk Characterization /
Thermal Properties /
Mechanical Properties /
Optical Properties /
Electrical Properties /
Chitosan Physics /
Physical Properties and Characterization /
Structure and Property Relationship /
Biological Properties of Chitosan /
Biodegradability /
Biocompatibility /
Anti-Microbial Activity /
Chitosan Application in Tissue Engineering /
Scaffold Fabrication Techniques /
Chitosan-Based Scaffolds for Tissue Engineering Applications /
Chitosan Application in Drug Delivery /
Advantages of Absorbable Poly(a-Ester)s /
Polylactides, Polyglycolides, and Copolymers Thereof /
Structure and Characteristics /
Processing /
Bacterial and Other Recombinant Polyesters /
Synthesis and Characterization /
Synthesis /
Characterization /
Impact of Composition on Polyurethane Properties /
Poly(Ether Urethanes) /
Poly(Carbonate Urethanes) /
Poly(Ether Ester Urethanes) /
Poly(Siloxane Urethanes) /
Polyurethane and Natural Polymers /
Polyurethane Composites /
Surface-Modified Polyurethanes /
Phase Separation Behavior /
Calcification /
Polyurethane Applications /
Drug Delivery /
Tissue Engineering /
Polyurethane Medical Devices /
Conclusion /
Synthesis of PEAs /
Design of PEAs with a Given Microstructure /
Hyperbranched PEAs /
Liquid Crystals and Rigid-Chain PEAs /
PEAs from Renewable Sources /
Carbohydrate Derivatives /
PEAs from Vegetable Oils and Fatty Diacids /
PEAs Derived from a-Amino Acids and Their Applications in the Biomedical Field /
Miscellaneous Applications of PEAs /
Scaffolds from Electroactive Samples and Electrospun Nanofibres /
Applications of Biodegradable Polyphosphazenes in Tissue Engineering /
Bone Tissue Regeneration /
Soft Tissue Regeneration /
Applications of Biodegradable Polyphosphazenes in Drug Delivery /
Conclusions and Future Trends /
Synthesis of "Pseudo" Poly(Amino Acid) /
Ester-Based "Pseudo" Poly(Amino Acids) /
Synthesis of Ester-Based "Pseudo" Poly(Amino Acids) /
Applications of Ester-Based "Pseudo" Poly(Amino Acids) /
Amide-Based "Pseudo" Poly(Amino Acids) /
Applications Poly(Amides) as "Pseudo" Poly(Amino Acids) /
Carbonate-Based "Pseudo" Poly(Amino Acids) /
Synthesis of Carbonate-Based "Pseudo" Poly(Amino Acids) /
Applications of Carbonate-Based "Pseudo" Poly(Amino Acids) /
Urethane-Based "Pseudo" Poly(Amino Acids) /
Synthesis of Urethane-Based "Pseudo" Poly(Amino Acids) /
Applications of Urethane-Based "Pseudo" Poly(Amino Acids) /
Biomedical Applications /
Polymer-Drug Conjugates /
Particulate-Associated Systems /
Polymer-Oligonucleotide Complexes /
Hydrogels /
Polyacetals in Tissue Engineering /
Current Clinical Strategies /
Biomaterials /
Synthetic Polymers /
Naturally-Derived Scaffolds /
Extracellular Matrix-Based Materials /
Cell Sources /
Cells of Adipose Tissue /
Adult Stem Cells /
Embryonic Stem Cells /
Induced Pluripotent Stem Cells /
Discussion /
Divergent Approach /
Convergent Approach /
Dendrimer Types /
PAMAM Dendrimers /
PPI Dendrimers /
Carbohydrate Dendrimers /
Triazine Dendrimers /
Peptide Dendrimers /
Miscellaneous /
Drug Loading in Dendrimers /
Non-Covalent Interactions /
Covalent Interactions /
B
Structural Compatibility and Mechanical Durability of Polymeric Prostheses /
Applications of Polymeric Biomaterials in Implantable Prostheses /
Cardiovascular Applications /
Orthopaedic Applications /
Ophthalmologic Applications /
Dental Applications /
Emerging Classes of Polymeric Biomaterials for Implantable Prostheses /
Anti-Fouling Polymeric Coatings /
Polymeric Surfaces to Direct Biological Responses /
Shape-Memory Polymers /
Conclusion and Perspectives /
Mechanical/Thermal Properties of Polymers /
Stress-Strain /
Viscoelastic /
Differential Scanning Calorimetry /
Surface and Morphological Characterization of Polymers /
Morphology /
Molecular Weight and Particle Size /
Surface Characterization /
Biocompatibility Testing of Polymeric Materials /
Regulatory Guidelines for Biocompatibility Testing /
Biodegradable Polymers /
In Vitro Cytotoxicity Assessment /
In Vivo Biocompatibility Evaluation /
In Vitro Dissolution Testing Methods for Polymeric Formulations /
Regulatory Guidelines and In Vitro-In Vivo Correlation /
In Vitro Dissolution Testing for Microspheres /
In Vitro Dissolution Testing for Nanoparticles /
In Vitro Dissolution Testing for In Situ Gel Formulations /
Natural Polymers in Tissue Engineering and Regenerative Medicine /
Proteins as Biomaterials /
Polysaccharides as Biomaterials /
Synthetic Polymers in Tissue Engineering and Regenerative Medicine /
Poly(a-Esters) /
Polyurethanes /
Polyphosphazenes /
Polyanhydrides /
Poly(propylene Fumarate) /
Poly(ethylene Glycol) /